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Table 1 Participant demographics, clinical scores, peripheral cytokine and hormone levels

From: Investigating the potential of a prematurely aged immune phenotype in severely injured patients as predictor of risk of sepsis

 

Healthy controls (n = 57)

Non sepsis trauma patients (n = 18)

Sepsis trauma patients (n = 37)

p value

Age (years)

39.67 ± 18.01

36.43 ± 16.03

46.15 ± 20.33

P = .37

Males (%)

50 ( 87.77%)

13 (72.77%)

31 (83.78%)

x

Injury severity score (ISS)

X

22.56 ± 9.67

27.72 ± 13.36

p = .27

NISS score

X

29.00 ± 11.73

36.19 ± 15.82

P = .19

APACHE score

X

18.00 ± 8.83

25.79 ± 6.74

p = .002

SOFA score

X

6.00 ± 2.77

10.59 ± 3.23

P < .0001

SAPS2 score

X

39.07 ± 19.45

55.24 ± 12.02

p = .003

ICU length of stay (days)

X

5.94 ± 8.10

17.18 ± 12.76

P < .0001

Ventilator days

X

4.00 ± 7.02

14.57 ± 12.50

P = .007

Hospital length of stay

X

23.87 ± 16.52

67.31 ± 46.19

P < .0001

CRP (mg/ml)

2.25 ± 1.77

113.2 ± 101.8

218.0 ± 77.71

P < .0001

IL6 (pg/ml)

5.42 ± 4.3

78.75 ± 101.8

566.9 ± 112.29

P < .0001

TNF (pg/ml)

0.39 ± 0.66

2.15 ± 2.28

7.18 ± 13.94

P < .0001

IL10(pg/ml)

2.35 ± 4.42

6.07 ± 10.25

10.42 ± 18.09

P = .004