Fig. 4
EV inflammatory proteins are associated with sex and poverty status. Plasma EVs from individuals in the frailty cohort were lysed and analyzed in a multiplex proximity extension assay (n = 177). Normalized protein levels (NPL, which is in a log2 scale) are shown. Linear regression was used to determine the relationship between EV protein levels and frailty status, accounting for sex, race, and poverty status (n = 177). A EV inflammatory proteins that had a significant association with sex and poverty status are plotted. The plots show the linear regression values ± standard error of the estimated values. B CXCL6 levels were significantly different with poverty status