Table 3 PC score differences and Euclidean distance (in the space defined by PCs 1 and 2) between treatments and control (untreated cells) for cytokine production. We observe a cluster of adjuvants (NP + Mi + CpG, R848, MPLA, CpG, LPS, and NP + R848 + Mi) that may lead to greater cytokine production than other adjuvants
Adjuvants | PC1(Adjuv)-PC1(Media) | PC2(Adjuv)-PC2(Media) | Distance(PC1,PC2) |
|---|---|---|---|
FLA-BS | 1.15 | 0.14 | 1.16 |
Micelles | 1.25 | 0.54 | 1.37 |
MDP | 1.39 | 0.32 | 1.42 |
CDN | 1.3 | 0.62 | 1.44 |
NP | 1.53 | −0.24 | 1.55 |
NP + Mi + CDN | 2.16 | 0.68 | 2.27 |
NP + Mi + CpG | 4.66 | 0 | 4.66 |
R848 | 5.27 | 0.07 | 5.27 |
MPLA | 5.52 | 0.24 | 5.53 |
CpG | 5.51 | 0.89 | 5.59 |
NP + Mi + R848 | 5.89 | −1.37 | 6.05 |
LPS | 6.11 | 0.34 | 6.12 |