Table 4 PCA for cytokines associated with T cell activation (CD4⁺ Tfh and CD8⁺ memory). Shown are PC score differences and Euclidean distance (in the space defined by PC1 and PC2) between treatments and control (untreated cells). We observed a cluster of adjuvants (NP + Mi + CpG, R848, NP + Mi + R848, CpG, MPLA, and LPS) that may have greater production of cytokines associated with T cell activation

From: “Just right” combinations of adjuvants with nanoscale carriers activate aged dendritic cells without overt inflammation