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Fig. 2 | Immunity & Ageing

Fig. 2

From: Glycyrrhizic acid inhibits myeloid differentiation of hematopoietic stem cells by binding S100 calcium binding protein A8 to improve cognition in aged mice

Fig. 2

Glycyrrhizic acid promoted differentiation of Lin−CD117+ HSCs toward B cells in vitro. A Schematic design of Lin−CD117+ HSCs co-cultured with OP9 cells for directed differentiation to B cells. B Representative FACS plots of CD45R/B220+ B cells and CD11b+ cells following differentiation of Lin−CD117+ HSCs co-cultured with OP9 cells. C Bar graph of statistical results of CD45R/B220+ B cells and CD11b+ cells in co-cultures following differentiation of Lin−CD117.+ HSCs with OP9 cells. Data represent mean ± SEM. n = 3, **P < 0.01, *P < 0. 05

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