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Fig. 2 | Immunity & Ageing

Fig. 2

From: Hemagglutinin virus-like particles incorporated with membrane-bound cytokine adjuvants provide protection against homologous and heterologous influenza virus challenge in aged mice

Fig. 2

Induction of IgG antibodies by HA-VLP and HA-VLP-Cyt vaccines. Aged (A-D) and young (E-H) BALB/c mice (n= 6/group) were immunized with 1 µg (A, E), 3 µg (B, F) or 6 µg (C, G) of HA-VLP or HA-VLP-Cyt. Mouse sera were collected at 2 weeks after prime or boost immunization. (D, H) IgG antibody responses to A/PR8 virus were measured in prime or boost immune sera and quantified in 1:1,000 sera. Error bars indicate mean ± SEM. * p<0.05; *** p<0.001

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