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Fig. 3 | Immunity & Ageing

Fig. 3

From: Hemagglutinin virus-like particles incorporated with membrane-bound cytokine adjuvants provide protection against homologous and heterologous influenza virus challenge in aged mice

Fig. 3

HA-VLP-Cyt vaccine induces A/PR8 specific IgG2a antibody responses at a higher dose in aged mice. Aged (A-C) and young (D-F) BALB/c mice (n= 6/group) received boost dose of HA-VLP or HA-VLP-Cyt. IgG1 (A, D) and IgG2a (B, E) antibody responses to A/PR8 2 weeks after 3 µg or 6 µg of HA-VLP or HA-VLP-Cyt inoculation. (C, F) A/PR8 specific IgG1 and IgG2a antibodies levels were quantified in 1:1,000 boost sera. Error bars indicate mean ± SEM. * p<0.05. 3 µg HA-VLP-Cyt and 6 µg HA-VLP-Cyt groups were compared

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Immunity & Ageing

ISSN: 1742-4933

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