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Fig. 5 | Immunity & Ageing

Fig. 5

From: Hemagglutinin virus-like particles incorporated with membrane-bound cytokine adjuvants provide protection against homologous and heterologous influenza virus challenge in aged mice

Fig. 5

HA-VLP and HA-VLP-Cyt vaccine-induced antibody inhibits hemagglutination of homologous but not heterologous viruses. HAI titers against the viruses (A/PR8, A/WSN, and A/Cal) were determined in sera from aged (A) and young (B) mice (n= 6/group) at 2 weeks after boost immunization with HA-VLP or HA-VLP-Cyt. 1 µg, 3 µg or 6 µg of each HA-VLP and HA-VLP-Cyt were administered. The statistical significances were determined using two-way ANOVA and indicated in *** P < 0.001. Error bars indicate mean ± SEM

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