Fig. 6

Reduced CD11b⁺Gr1^high and increased CD163⁺ CX3CR1⁺ and/or CD11b⁺ cell populations in male GlaKO DRG. A Flow cytometry analysis of myeloid cells in GlaKO and control DRG cell suspensions from 20 - 24 weeks old male mice. Representative scatter plots and histograms of CD11b and Gr1 evidencing a reduced fraction of CD11b⁺Gr1^high cells in GlaKO DRG. B Higher TLR4 expression and (C) enriched CD163⁺ CX3CR1⁺ and/or CD11b⁺ cells in GlaKO as compared to control DRG. D Dimensional reduction using tSNE and clustering analysis from each myeloid cell population identified in (A), (B) and (C). Pooled samples from 3 mice, wt male samples n = 3, GlaKO male samples n = 3