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Table 2 Zinc ion bioavailability, corticosterone, thymulin and TECs number and proliferation in young, old and very old mice

From: Are zinc-bound metallothionein isoforms (I+II and III) involved in impaired thymulin production and thymic involution during ageing?

Mice Thymulin activity (log-2) AT/TT (log-2 (zinc ion bioavailability) Corticosterone (ng/ml) Plasma zinc (μg/dl) % TECs TECs proliferation (cpm)
Young 5.5 ± 0.5 1.1 ± 0.3 153 ± 18.3 110 ± 11 53 ± 11 750 ± 25
Old 1.07 ± 0.3* 3.0 ± 0.3** 265 ± 16.6** 80 ± 5.7++ 21 ± 7** 227 ± 34**
Very old 2.5 ± 0.3+ 1.0 ± 0.3 180 ± 12.4+ 87 ± 43++ 40 ± 12+ 450 ± 39+
  1. *p < 0.001 when compared to young mice; +p < 0.05 when compared to old mice;
  2. **p < 0.01 when compared to young and very old mice; ++p < 0.01 when compared to young mice.