As a result of the significant disruption that is being caused by the COVID-19 pandemic we are very aware that many researchers will have difficulty in meeting the timelines associated with our peer review process during normal times. Please do let us know if you need additional time. Our systems will continue to remind you of the original timelines but we intend to be highly flexible at this time.
Editors' Pick: Functional conservation in genes and pathways linking ageing and immunity
The molecular basis of ageing and longevity is a subject of perennial interest, as is the “immunological theory of ageing” first proposed by Roy Walford in the 1960´s. This review paper scrutinizes the evidence for an intimate relationship between the immune system and organismal ageing, taking a very broad view of its genetic basis comparing humans, the mouse Mus musculus, the fruitfly Drosophila melanogaster, and the roundworm Caenorhabditis elegans. This survey revealed seven evolutionarily conserved signalling cascades, the insulin/TOR network, three MAPK (ERK, p38, JNK), JAK/STAT, TGF-β, and Nf-κB pathways that act pleiotropically and link immunity and lifespan across these species. Intrinsic functional conservation in these pathways between C. elegans, D. melanogaster, and mammals is proposed as a framework linking basic immune-ageing processes.
Thematic series: Immunity, Metabolism and Aging
Due to the cancellation of the meeting “Immunity, Metabolism and Aging”, scheduled to take place in Modena (Italy), September 24-25 2020, for the difficult circumstances created by the global COVID-19 pandemic, we have suggested a "Symposium-in-Writing" whereby the speakers that have already accepted to give a talk in Modena will submit a paper to this special issue of the journal Immunity & Ageing. Daniela Frasca and Andrea Cossarizza
COVID-19 and impact on peer review
Announcing the launch of In Review
Immunity & Ageing, in partnership with Research Square, is now offering In Review. Authors choosing this free optional service will be able to:
- Share their work with fellow researchers to read, comment on, and cite even before publication
- Showcase their work to funders and others with a citable DOI while it is still under review
- Track their manuscript - including seeing when reviewers are invited, and when reports are received
Articles
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Systemic transplantation of adult multipotent stem cells prevents articular cartilage degeneration in a mouse model of accelerated ageing
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Is mechanical loading essential for exercise to preserve the aging immune system?
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A potential association between immunosenescence and high COVID-19 related mortality among elderly patients with cardiovascular diseases
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The age again in the eye of the COVID-19 storm: evidence-based decision making
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Effects of ebselen and N-acetyl cysteine on replicative aging of primary human fibroblast strains
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Melatonin, immune function and aging
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Total and specific serum IgE decreases with age in patients with allergic rhinitis, asthma and insect allergy but not in patients with atopic dermatitis
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The Interleukin-6 inflammation pathway from cholesterol to aging – Role of statins, bisphosphonates and plant polyphenols in aging and age-related diseases
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The immune system and the impact of zinc during aging
2020
Thematic series
Immunity, Metabolism and Aging
Daniela Frasca and Andrea Cossarizza
2016
Thematic series
Nutrigerontology: a key for achieving successful ageing and longevity
Collection published: April/ May 2016
2015
Cross journal collection
Day of Immunology 2015
Collection published: 28 April 2015
2012
Thematic series
Positive biology: the centenarian lesson
Immunity & Ageing
Collection published: 23 April 2012
Aims and scope
Immunity & Ageing, published since 2004, is a specialist open access journal dedicated to increasing knowledge about the impact of ageing on immune systems, the influence of aged immune systems on organismal well-being and longevity, and the potential for interventions to increase lifespan. The journal welcomes submissions dealing with any aspect of ageing in human and model organisms that relates to immune function.
All articles undergo rapid and rigorous peer-review and all accepted articles are published open access to provide the highest visibility for authors’ work.
The increasing realization that immune ageing and organismal ageing are intimately inter-related puts the immune system centre-stage in our efforts to understand and manipulate the ageing process and Immunity & Ageing continues to offer a specialized conduit for dissemination of new knowledge in this increasingly important arena.
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About the Editors
Graham Pawelec
Graham Pawelec is Professor of Experimental Immunology at the University of Tübingen, Germany, where he led the Tübingen Ageing and Tumour Immunology (TATI) group from 1999 to 2017. He is currently affiliated with the Health Sciences North Research Institute of Canada, Sudbury, ON, and is a Visiting Professor at Nottingham Trent University, King´s College London, and Manchester University, UK. His research interests remain centered on immunogerontology in the context of cancer immunology and immunotherapy, and vaccination.
Nan-ping Weng
Nan-ping Weng is tenured senior investigator, Chief of Lymphocyte Differentiation Section, Laboratory of Molecular Biology and Immunology at the National Insitute on Aging (NIA), NIH. He joined the Laboratory of Immunology at the NIA as a tenure-track investigator in 1997 and has been tenured senior investigator since 2006. His laboratory focuses on the understanding of molecular and cellular mechanisms of T cell differentiation and age-associated decline of T cell functions.
Founding Editor
Professor Calogero Caruso MD Professor of General Pathology and Director of Palermo University Medical School “Ippocrate”
Whether your interests are immunological aspects of ageing, age-related diseases and longevity, this journal can serve as an appropriate venue.
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Annual Journal Metrics
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Speed
61 days to first decision for reviewed manuscripts only
51 days to first decision for all manuscripts
119 days from submission to acceptance
16 days from acceptance to publicationCitation Impact
2.804 - 2-year Impact Factor
3.308 - 5-year Impact Factor
0.949 - Source Normalized Impact per Paper (SNIP)
1.126 - SCImago Journal Rank (SJR)Usage
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343 Altmetric mentions