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The attractive concept of limited "immunological space” whereby senescent and exhausted cells crowd out functional cells in older individuals has proven difficult to substantiate in humans where most studies are limited to peripheral blood. Naismith et al. now demonstrate that this “crowding effect” is observed in the rarely-studied human bone marrow environment and potentially results in lower titers of pathogen-specific antibodies in the blood, implying an important clinical relevance of this phenomenon
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Cross journal collection
Day of Immunology 2015
Collection published: 28 April 2015
Thematic series
Positive biology: the centenarian lesson
Immunity & Ageing
Collection published: 23 April 2012
Immunity & Ageing, published since 2004, is a specialist open access journal dedicated to increasing knowledge about the impact of ageing on immune systems, the influence of aged immune systems on organismal well-being and longevity, and the potential for interventions to increase healthspan. The journal welcomes submissions dealing with any aspect of ageing in human and model organisms that relates to immune function.
All articles undergo rapid and rigorous peer-review and all accepted articles are published open access to provide the highest visibility for authors’ work.
The increasing realization that immune ageing and organismal ageing are intimately inter-related puts the immune system centre-stage in our efforts to understand and manipulate the ageing process and Immunity & Ageing continues to offer a specialized conduit for dissemination of new knowledge in this increasingly important arena.
Graham Pawelec is Professor of Experimental Immunology at the University of Tübingen, Germany, where he led the Tübingen Ageing and Tumour Immunology (TATI) group from 1999 to 2017. He is currently affiliated with the Health Sciences North Research Institute of Canada, Sudbury, ON, and is a Visiting Professor at Nottingham Trent University, King´s College London, and Manchester University, UK. His research interests remain centered on immunogerontology in the context of cancer immunology and immunotherapy, and vaccination.
Nan-ping Weng is tenured senior investigator, Chief of Lymphocyte Differentiation Section, Laboratory of Molecular Biology and Immunology at the National Insitute on Aging (NIA), NIH. He joined the Laboratory of Immunology at the NIA as a tenure-track investigator in 1997 and has been tenured senior investigator since 2006. His laboratory focuses on the understanding of molecular and cellular mechanisms of T cell differentiation and age-associated decline of T cell functions.
Professor Calogero Caruso MD Professor of General Pathology and Director of Palermo University Medical School “Ippocrate”
Whether your interests are immunological aspects of ageing, age-related diseases and longevity, this journal can serve as an appropriate venue.
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Speed
45 days to first decision for reviewed manuscripts only
41 days to first decision for all manuscripts
97 days from submission to acceptance
24 days from acceptance to publication
Citation Impact
4.250 - 2-year Impact Factor
3.324 - 5-year Impact Factor
0.978 - Source Normalized Impact per Paper (SNIP)
1.446 - SCImago Journal Rank (SJR)
Usage
141,113 Downloads
112 Altmetric Mentions
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