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Immune-inflammatory responses in the Elderly: an update

A long life in a healthy, vigorous, youthful body has always been one of humanity’s greatest dreams. In this collection, anti-ageing strategies have been discussed based on the control of immune-inflammatory responses, aimed not only to slow the ageing process, but also to delay or avoid the onset of age-related diseases such as cancer or combat infectious diseases. Intriguingly, there is a connection between these responses and nutrient sensing pathways already known to delay age-related diseases and promote longevity.


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Thematic series
Nutrigerontology: a key for achieving successful ageing and longevity
Collection published: April/ May 2016



Cross journal collection
Day of Immunology 2015
Collection published: 28 April 2015


Thematic series
Positive biology: the centenarian lesson
Immunity & Ageing
Collection published: 23 April 2012

Aims and scope

"Ageing seems to be the only available way to live a long life." Daniel Auber

Immunity & Ageing publishes articles on all aspects of ageing examined from an immunological point of view.

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About the Editor

Professor Calogero Caruso MD is an immunopathologist whose research interests are in biogerontology, in particular in genotypic and phenotypic determinants involved in attainment of successful and unsuccessful ageing. In this field, his group was the first to demonstrate the role of cytokine anti-inflammatory genotype in achieving longevity, turning the attention of the related scientific community towards the opposite role of inflammatory mediator genotypes in longevity and age-related diseases, including Alzheimer’s disease.

He is currently Full Professor of General Pathology and Director of Palermo University Medical School “Ippocrate”. As previously stated, his laboratory studies several aspects of ageing, in particular the role of B immunosenescence and immunogenetics in longevity (the model of centenarians and of their offspring) and Alzheimer’s diseases (the role of systemic inflammation and diet).

I am delighted to be the Editor-in-Chief of Immunity & Ageing devoted to the role of natural and acquired immunity in successful and unsuccessful ageing of both human beings and experimental models. Whether your interests are immunological aspects of ageing, age-related diseases and longevity, this journal can serve as an appropriate venue.


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