Figure 12
T-cell differentiation into functionally different T-cell subsets and age-related defects in T-cell activation. Th1: T helper 1 cells; Th2: T helper 2 cells; Th17: T helper 17 cells; Tbet, GATA3, ROR, FoxP3: different transcriptional factors; IL: interleukin; TGF-β: transforming growth factor beta.