Figure 8From: Immunosenescence in vertebrates and invertebratesInteraction of T cell and dendritic cell leading to T-cell activation, clonal expansion and differentiation. If any of the activation requirements are detrimentally affected by ageing, immune responses will be compromised. Additionally, age-related deleterious changes in memory cells are to be expected. DC: dendritic cells; TC: T cells; Treg: regulatory T cells; CD: cluster of differentiation.Back to article page