Table 2 Cytokines profile
From: Septic shock in older people: a prospective cohort study
Young | Elderly | Group A vs. B | |||||
|---|---|---|---|---|---|---|---|
Control n=36 | Septic shock (group A) n=21 | p-value | Control n=8 | Septic shock (group B) n=8 | p-value | p-value | |
IL-1α | 31 ± 42 | 100 ± 82 | 0.000 | 27 ± 27 | 75 ± 82 | 0.270 | 0.242 |
IL-1β | 2.50 ± 2.93 | 7.09 ± 7.11 | 0.007 | 1.12 ± 1.35 | 4.37 ± 6.98 | 0.480 | 0.148 |
IL-1 RA | 36 ± 47 | 192 ± 295 | 0.001 | 31 ± 33 | 145 ± 292 | 0.114 | 0.317 |
IL-2 | 9.00 ± 6.74 | 13 ± 10 | 0.121 | 4.12 ± 2.10 | 9.62 ± 5.52 | 0.023 | 0.508 |
IL-3 | 2.08 ± 2.44 | 2.61 ± 3.33 | 0.849 | 0.62 ± 0.51 | 2.25 ± 2.54 | 0.070 | 0.899 |
IL-4 | 8.55 ± 10.60 | 32 ± 48 | 0.007 | 3.87 ± 4.91 | 16.00 ± 22.35 | 0.093 | 0.334 |
IL-5 | 2.19 ± 3.24 | 7.19 ± 9.26 | 0.010 | 0.50 ± 1.06 | 2.87 ± 3.44 | 0.082 | 0.208 |
IL-6 | 37 ± 63 | 1641 ± 3195 | 0.000 | 32 ± 39 | 1666 ± 3590 | 0.036 | 0.884 |
IL-7 | 11 ± 8.26 | 40 ± 39 | 0.000 | 5.62 ± 3.46 | 34.75 ± 48.70 | 0.002 | 0.393 |
IL-8 | 29 ± 25 | 806 ± 2819 | 0.000 | 26.25 ± 22.24 | 1695 ± 4602 | 0.016 | 0.354 |
IL-9 | 2.08 ± 2.37 | 4.52 ± 5.06 | 0.044 | 0.50 ± 1.06 | 4.25 ± 6.11 | 0.043 | 0.489 |
IL-10 | 12 ± 16 | 626 ± 2195 | 0.000 | 38 ± 78 | 480 ± 1079 | 0.012 | 0.575 |
IL-12p40 | 39 ± 44 | 111 ± 80 | 0.000 | 31 ± 34 | 141 ± 214 | 0.206 | 0.464 |
IL-12p70 | 7.19 ± 4.79 | 20.61 ± 20.09 | 0.002 | 4.50 ± 2.72 | 10.50 ± 8.79 | 0.423 | 0.195 |
IL-13 | 4.86 ± 6.51 | 14.90 ± 32.48 | 0.119 | 1.37 ± 1.06 | 10.87 ± 16.12 | 0.097 | 0.583 |
IL-15 | 7.38 ± 6.23 | 20.52 ± 25.30 | 0.001 | 4.00 ± 3.20 | 16.62 ± 18.92 | 0.011 | 0.558 |
IL-17 | 2.88 ± 2.43 | 8.66 ± 6.31 | 0.000 | 1.87 ± 1.45 | 6.87 ± 5.46 | 0.018 | 0.493 |
IFNα | 67 ± 42 | 110 ± 58 | 0.000 | 195 ± 402 | 78 ± 38 | 0.270 | 0.150 |
IFNy | 7.83 ± 4.45 | 40.09 ± 52.41 | 0.000 | 6.25 ± 5.67 | 30.87 ± 36.56 | 0.013 | 0.574 |
TFNα | 19 ± 21 | 111 ± 207 | 0.000 | 23 ± 20 | 81 ± 102 | 0.016 | 0.770 |