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Table 2 Cytokines profile

From: Septic shock in older people: a prospective cohort study

  Young Elderly Group A vs. B
Control n=36 Septic shock (group A) n=21 p-value Control n=8 Septic shock (group B) n=8 p-value p-value
IL-1α 31 ± 42 100 ± 82 0.000 27 ± 27 75 ± 82 0.270 0.242
IL-1β 2.50 ± 2.93 7.09 ± 7.11 0.007 1.12 ± 1.35 4.37 ± 6.98 0.480 0.148
IL-1 RA 36 ± 47 192 ± 295 0.001 31 ± 33 145 ± 292 0.114 0.317
IL-2 9.00 ± 6.74 13 ± 10 0.121 4.12 ± 2.10 9.62 ± 5.52 0.023 0.508
IL-3 2.08 ± 2.44 2.61 ± 3.33 0.849 0.62 ± 0.51 2.25 ± 2.54 0.070 0.899
IL-4 8.55 ± 10.60 32 ± 48 0.007 3.87 ± 4.91 16.00 ± 22.35 0.093 0.334
IL-5 2.19 ± 3.24 7.19 ± 9.26 0.010 0.50 ± 1.06 2.87 ± 3.44 0.082 0.208
IL-6 37 ± 63 1641 ± 3195 0.000 32 ± 39 1666 ± 3590 0.036 0.884
IL-7 11 ± 8.26 40 ± 39 0.000 5.62 ± 3.46 34.75 ± 48.70 0.002 0.393
IL-8 29 ± 25 806 ± 2819 0.000 26.25 ± 22.24 1695 ± 4602 0.016 0.354
IL-9 2.08 ± 2.37 4.52 ± 5.06 0.044 0.50 ± 1.06 4.25 ± 6.11 0.043 0.489
IL-10 12 ± 16 626 ± 2195 0.000 38 ± 78 480 ± 1079 0.012 0.575
IL-12p40 39 ± 44 111 ± 80 0.000 31 ± 34 141 ± 214 0.206 0.464
IL-12p70 7.19 ± 4.79 20.61 ± 20.09 0.002 4.50 ± 2.72 10.50 ± 8.79 0.423 0.195
IL-13 4.86 ± 6.51 14.90 ± 32.48 0.119 1.37 ± 1.06 10.87 ± 16.12 0.097 0.583
IL-15 7.38 ± 6.23 20.52 ± 25.30 0.001 4.00 ± 3.20 16.62 ± 18.92 0.011 0.558
IL-17 2.88 ± 2.43 8.66 ± 6.31 0.000 1.87 ± 1.45 6.87 ± 5.46 0.018 0.493
IFNα 67 ± 42 110 ± 58 0.000 195 ± 402 78 ± 38 0.270 0.150
IFNy 7.83 ± 4.45 40.09 ± 52.41 0.000 6.25 ± 5.67 30.87 ± 36.56 0.013 0.574
TFNα 19 ± 21 111 ± 207 0.000 23 ± 20 81 ± 102 0.016 0.770