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Table 1 Cytokines production by monocytes or PBMC from young subjects

From: Proinflammatory profile of in vitro monocytes in the ageing is affected by lymphocytes presence

Cytokines

Cellular type

Production type

Median

Minimum

Maximum

1th quartile

3th quartile

TNF-α

Monocyte

Basal

0.0

0.0

24.4

0.0

0.0

LPS

246.6

34.5

1486.5

182.8

97.6

PBMC

Basal

2.5

0.0

19.0

0.0

10.4

LPS

341.6

70.8

1165.8

270.3

728.7

IL-6

Monocyte

Basal

2.6

0.0

68.1

0.0

8.9

LPS

175.8

50.5

282.0

138.3

186.1

PBMC

Basal

0.0

0.0

123.2

0.0

6.4

LPS

139.6

0.0

266.6

116.7

218.2

IL-1β

Monocyte

Basal

0.0

0.0

0.1

0.0

0.0

LPS

69.6

15.3

173.7

37.5

173.7

PBMC

Basal

0.0

0.0

1.0

0.0

0.0

LPS

17.9

0.0

113.8

0.0

31.5

CXCL-8

Monocyte

Basal

173.1

48.7

288.8

130

240.1

LPS

279.5

177.3

297.7

252.3

290.9

PBMC

Basal

144.8

64.0

215.1

118.6

185.4

LPS

229.8

218.4

305.4

219.8

303.0

MCP-1

Monocyte

Basal

6.4

0.0

190.5

0.0

39.8

LPS

48.2

0.0

241.2

0.0

148.4

PBMC

Basal

25.9

5.9

412.4

12.2

97.5

LPS

85.0

0.0

415.3

29.1

172.7

TGF-β

Monocyte

Basal

621.2

621.1

621.4

621.1

621.3

LPS

621.2

621.0

621.6

621.1

621.2

PBMC

Basal

51.7

8.9

220.5

25.8

130.9

LPS

567.2

110.2

690.5

223.1

587.9

IL-10

Monocyte

Basal

0.0

0.0

5.9

0.0

0.0

LPS

149.3

33.8

654.8

55.4

323.8

PBMC

Basal

0.0

0.0

11.8

0.0

0.0

LPS

129.1

47.0

274.1

102.7

195.6

  1. Values showed by median, minimum, maximum, 1th and 3th quartiles obtained by descriptive statistical analysis (Statsoft Software Inc. Tulsa, Ok, USA).