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Table 1 Comparison of SARS-CoV induced histologic changes in the lungs of aged and juvenile monkeys

From: Severe acute respiratory syndrome-coronavirus infection in aged nonhuman primates is associated with modulated pulmonary and systemic immune responses

  Value
Group No. of animals Gradea Venous thrombosis Perivascular cuffing Alveolitis Interstitial pneumonia
Aged 5 d.p.i. 5 Severity 0 1.8 1.2 0.4
Incidence 0% 100% 80% 40%
Juvenile 5 d.p.i. 11 Severity 0.27 1.2 1 0.45
Incidence 18% 82% 73% 27%
Aged 10 d.p.i. 5 Severity 0 1.6 1.4 0.2
Incidence 0% 100% 80% 20%
Juvenile 10 d.p.i. 6 Severity 0.33 1.7 1.3 1.5
Incidence 17% 100% 100% 83%
Aged mock 3 Severity 0 0.33 0 0
Incidence 0% 33% 0% 0%
Juvenile mock 2 Severity 0 0 0 0
   Incidence 0% 0% 0% 0%
  1. aSeverity is the average grade for the group (0 = normal, 1 = minimal, 2 = mild, 3 = moderate, 4 = marked); incidence is the percentage of the group affected.