Table 1 Comparison of SARS-CoV induced histologic changes in the lungs of aged and juvenile monkeys
Value | ||||||
|---|---|---|---|---|---|---|
Group | No. of animals | Gradea | Venous thrombosis | Perivascular cuffing | Alveolitis | Interstitial pneumonia |
Aged 5 d.p.i. | 5 | Severity | 0 | 1.8 | 1.2 | 0.4 |
Incidence | 0% | 100% | 80% | 40% | ||
Juvenile 5 d.p.i. | 11 | Severity | 0.27 | 1.2 | 1 | 0.45 |
Incidence | 18% | 82% | 73% | 27% | ||
Aged 10 d.p.i. | 5 | Severity | 0 | 1.6 | 1.4 | 0.2 |
Incidence | 0% | 100% | 80% | 20% | ||
Juvenile 10 d.p.i. | 6 | Severity | 0.33 | 1.7 | 1.3 | 1.5 |
Incidence | 17% | 100% | 100% | 83% | ||
Aged mock | 3 | Severity | 0 | 0.33 | 0 | 0 |
Incidence | 0% | 33% | 0% | 0% | ||
Juvenile mock | 2 | Severity | 0 | 0 | 0 | 0 |
Incidence | 0% | 0% | 0% | 0% | ||