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Table 4 Opsonophagocytic activity in young and elderly.

From: Immune response to pneumococcal polysaccharides 4 and 14 in elderly and young adults. I Antibody concentrations, avidity and functional activity

  

Pre-immune GMT (95% CI)

Post-immune GMT (95% CI)

P value

PPS4

Young

10.2 (4.43–15.97)

93.6 (-19.63–206.89)

0.001

 

Elderly

14.9 (2.74–27.12)

147.0 (-16.63–310.70)

0.001

PPS14

Young

16.7 (-33.03–66.36)

245.8 (82.50–409.05)

0.0004

 

Elderly

26.9 (-104.78–158.60)

265.03 (115.74–414.32)

0.0003

  1. Geometric mean titer of serotype specific opsonophagocytic activity in pre-and post-immunization serum, from young and elderly volunteers. Significance of increase from pre to post-immunization was calculated using two tailed paired students T-test.
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Immunity & Ageing

ISSN: 1742-4933

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