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Table 4 Opsonophagocytic activity in young and elderly.

From: Immune response to pneumococcal polysaccharides 4 and 14 in elderly and young adults. I Antibody concentrations, avidity and functional activity

   Pre-immune GMT (95% CI) Post-immune GMT (95% CI) P value
PPS4 Young 10.2 (4.43–15.97) 93.6 (-19.63–206.89) 0.001
  Elderly 14.9 (2.74–27.12) 147.0 (-16.63–310.70) 0.001
PPS14 Young 16.7 (-33.03–66.36) 245.8 (82.50–409.05) 0.0004
  Elderly 26.9 (-104.78–158.60) 265.03 (115.74–414.32) 0.0003
  1. Geometric mean titer of serotype specific opsonophagocytic activity in pre-and post-immunization serum, from young and elderly volunteers. Significance of increase from pre to post-immunization was calculated using two tailed paired students T-test.