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Table 1 Alterations in T cell compartments with age

From: Role of persistent CMV infection in configuring T cell immunity in the elderly

T cell
↑ CD45RO+ cells
↑ CD95+ cells
↓ CD28 expression
↑ CD152 expression
↑ inhibitory receptors expression
↓ signal transduction (rafts)
↓ cytokine production (IL-2)
↓ apoptosis of CD8 cells
↑ apoptosis of CD4 cells