Table 1 Alterations in T cell compartments with age
From: Role of persistent CMV infection in configuring T cell immunity in the elderly
T cell |
|---|
↑ CD45RO+ cells |
↑ CD95+ cells |
↓ CD28 expression |
↑ CD152 expression |
↑ inhibitory receptors expression |
↓ signal transduction (rafts) |
↓ cytokine production (IL-2) |
↓ apoptosis of CD8 cells |
↑ apoptosis of CD4 cells |