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Table 3 Drug use

From: Evidence of accelerated ageing in clinical drug addiction from immune, hepatic and metabolic biomarkers

PARAMETER

ADDICTS

MEDICAL

Dose & Duration

  

Cigarette Numbers

16.08 (10.87)

4.36 (8.12)***

Cigarette Duration (Yrs)

13.83 (8.62)

3.77 (8.145)***

Alcohol Size (g/d)

8.65 (21.51)

1.77 (10.23)***

Alcohol Duration (Yrs)

2.97 (5.84)

0.96 (3.08)***

Cannabis Size (g/d)

2.71 (5.25)

0.34 (1.56)***

Cannabis Duration (Yrs)

7.27 (7.57)

0.81 (3.24)***

Heroin Size (g/d)

0.57 (1.01)

0.00***

Heroin Duration (Yrs)

8.97 (6.92)

0.00***

Morphine Size (g/d)

0.05 (0.20)

0.00***

Morphine Duration (Yrs)

1.19 (4.12)

0.00***

Methadone Max. Dose

27.53 (47.19)

0.00***

Methadone Duration (Yrs)

1.21 (3.05)

0.00***

Amphetamine Size (g/d)

0.55 (1.51)

0.02 (0.15)***

Amphetamine Duration (Yrs)

1.89 (4.29)

0.19 (1.31)***

Dose-Duration Products

  

Cigarette Index (Cig-Yrs)

256.25 (217.70)

69.26 (164.68)****

Alcohol Index (g-Yrs)

73.49 (219.19)

21.89 (132.79)*

THC Index (g-Yrs)

28.99 (62.87)

3.31 (14.53)****

Heroin Index (g-Yrs)

5.92 (11.06)

0****

Morphine Index (g-Yrs)

0.39 (1.57)

0***

Methadone Index (mg-Yrs)

114.26 (373.82)

0****

Amphetamine Index (g-Yrs)

1.39 (10.17)

0.19 (1.31)****

  1. Data as Mean (± S.D.)
  2. * – P < 0.05
  3. *** – P < 0.001
  4. **** – P < 0.0001