Skip to main content

Advertisement

Table 1 Clinical and biochemical characteristics of the studied population

From: Endothelial nitric oxide synthase gene polymorphisms and cardiovascular damage in hypertensive subjects: an Italian case-control study

  Normotensives Hypertensives p<
Patients (n°) 67 127  
Women (%) 58 56  
Men (%) 42 44  
Age (years) 48.5 (40.0–55.0) 50.0 (44.0–57.0) 0.002
Weight (Kg) 77.4 (66.0–85.0) 80.0 (70.0–90.5) n.s.
High(cm) 1.7 (1.6–1.7) 1.7 (1.6–1.7) n.s.
BMI (Kg/m2) 27.1 (25.5–31.2) 29.3 (26.8–32.4) n.s.
WHR 0.9 (0.9–1.0) 0.9 (0.9–1.0) n.s.
SBP (mmHg) 127.5 (115.0–130.0) 140.0 (130.0–150.0) 0.001
DBP(mmHg) 80.0 (70.0–85.0) 90.0 (80.0–95.0) 0.001
MBP(mmHg) 94.2 (86.7–100.0) 106.7 (98.8–113.3) 0.001
BUN (mg/dl) 36.0 (31.0–39.0) 37.5 (33.3–44.0) n.s.
Creatinine (mg/dl) 0.8 (0.7–0.9) 0.8 (0.7–0.9) n.s.
Clearance (ml/min) 126.0 (100.3–153.0) 112.0 (88.1–140.0) n.s.
AER(mg/24 h) 53.4 (21.3–150.5) 73.6 (44.4–122.0) 0.05
LVM (g) 145.8 (118.2–176.8) 161.1 (143.4–192.0) 0.007
LVM/h2,7 35.7(31.7–43.0) 41.4 (36.0–49.5) 0.004
Insulin (μUI/ml) 8.0 (4.5–12.4) 10.5 (8.0–15.0) n.s.
  1. BMI: body mass index; WHR: waist/hip ratio; PAS: systolic artery pressure; PAD; diastolic artery pressure; PAM: media artery pressure; BUN: blood urea nitrogen; AER: albumin excretion rate; LVM: left ventricular mass; LVM/h2.7: left ventricular mass/high2.7.
  2. Data are presented as median (lower-upper quartiles)