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Table 1 Clinical and biochemical characteristics of the studied population

From: Endothelial nitric oxide synthase gene polymorphisms and cardiovascular damage in hypertensive subjects: an Italian case-control study

 

Normotensives

Hypertensives

p<

Patients (n°)

67

127

 

Women (%)

58

56

 

Men (%)

42

44

 

Age (years)

48.5 (40.0–55.0)

50.0 (44.0–57.0)

0.002

Weight (Kg)

77.4 (66.0–85.0)

80.0 (70.0–90.5)

n.s.

High(cm)

1.7 (1.6–1.7)

1.7 (1.6–1.7)

n.s.

BMI (Kg/m2)

27.1 (25.5–31.2)

29.3 (26.8–32.4)

n.s.

WHR

0.9 (0.9–1.0)

0.9 (0.9–1.0)

n.s.

SBP (mmHg)

127.5 (115.0–130.0)

140.0 (130.0–150.0)

0.001

DBP(mmHg)

80.0 (70.0–85.0)

90.0 (80.0–95.0)

0.001

MBP(mmHg)

94.2 (86.7–100.0)

106.7 (98.8–113.3)

0.001

BUN (mg/dl)

36.0 (31.0–39.0)

37.5 (33.3–44.0)

n.s.

Creatinine (mg/dl)

0.8 (0.7–0.9)

0.8 (0.7–0.9)

n.s.

Clearance (ml/min)

126.0 (100.3–153.0)

112.0 (88.1–140.0)

n.s.

AER(mg/24 h)

53.4 (21.3–150.5)

73.6 (44.4–122.0)

0.05

LVM (g)

145.8 (118.2–176.8)

161.1 (143.4–192.0)

0.007

LVM/h2,7

35.7(31.7–43.0)

41.4 (36.0–49.5)

0.004

Insulin (μUI/ml)

8.0 (4.5–12.4)

10.5 (8.0–15.0)

n.s.

  1. BMI: body mass index; WHR: waist/hip ratio; PAS: systolic artery pressure; PAD; diastolic artery pressure; PAM: media artery pressure; BUN: blood urea nitrogen; AER: albumin excretion rate; LVM: left ventricular mass; LVM/h2.7: left ventricular mass/high2.7.
  2. Data are presented as median (lower-upper quartiles)