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Table 3 Comparison of blood variables at pre- and post-intervention between the b240 and placebo groups

From: Oral intake of Lactobacillus pentosus strain b240 accelerates salivary immunoglobulin A secretion in the elderly: A randomized, placebo-controlled, double-blind trial

 

Pre-intervention

 

Post-intervention

 

Blood variable

Placebo group

(n = 40)

b240 group1

(n = 40)

P value

Placebo group

(n = 40)

b240 group1

(n = 40)

P value

Total protein (g/dL)

7.4 ± 0.4

7.2 ± 0.6

0.137

7.3 ± 0.4

7.2 ± 0.5

0.413

Albumin (g/dL)

4.4 ± 0.2

4.3 ± 0.2

0.115

4.4 ± 0.2

4.3 ± 0.3

0.381

Albumin/

globulin ratio

1.5 ± 0.2

1.5 ± 0.2

0.733

1.5 ± 0.2

1.5 ± 0.2

0.744

Total cholesterol (mg/dL)

221 ± 29

219 ± 35

0.722

221 ± 30

223 ± 37

0.814

Triglyceride (mg/dL)

105 ± 51

99 ± 53

0.631

101 ± 53

103 ± 50

0.895

Free fatty acid (mEq/L)

0.6 ± 0.2

0.6 ± 0.2

0.126

0.5 ± 0.2

0.5 ± 0.2

0.166

Fasting glucose (mg/dL)

95 ± 13

92 ± 12

0.355

95 ± 16

94 ± 16

0.863

Hemoglobin A1c (%)

5.2 ± 0.4

5.3 ± 0.4

0.536

5.3 ± 0.4

5.4 ± 0.4

0.663

Aspartate amino-transferase (U/L)

24.5 ± 7.2

25.7 ± 9.1

0.506

23.1 ± 8.6

23.6 ± 9.5

0.825

Alanine amino-transferase (U/L)

18.9 ± 7.9

20.4 ± 7.5

0.387

18.1 ± 10.1

18.3 ±7.2

0.939

γ-Glutamyl transpeptidase (U/L)

27.8 ± 18.3

28.7 ± 26.2

0.863

27.1 ± 21.4

29.4 ± 34.9

0.724

Alkaline phosphatase (U/L)

258 ± 74

265 ± 131

0.763

245 ± 67

262 ± 143

0.506

Lactate dehydrogenase (U/L)

216 ± 51

205 ± 62

0.386

194 ± 25

184 ± 27

0.113

Choline- esterase (U/L)

340 ± 50

328 ± 47

0.258

325 ± 48

319 ± 48

0.619

Total bilirubin (mg/dL)

0.6 ± 0.2

0.7 ± 0.3

0.058

0.7 ± 0.2

0.7 ± 0.3

0.315

Direct bilirubin (mg/dL)

0.2 ± 0.0

0.2 ± 0.1

0.122

0.2 ± 0.1

0.2 ± 0.1

0.752

Indirect bilirubin (mg/dL)

0.5 ± 0.1

0.5 ± 0.2

0.078

0.5 ± 0.2

0.6 ± 0.2

0.241

Urea nitrogen (mg/dL)

14.8 ± 3.6

15.1 ± 3.6

0.695

15.7 ± 4.5

15.9 ± 3.5

0.846

Uric acid (mg/dL)

4.8 ± 1.0

4.9 ± 1.0

0.771

5.0 ± 1.0

5.1 ± 1.2

0.983

Creatinine (mg/dL)

0.7 ± 0.2

0.7 ± 0.1

0.894

0.7 ± 0.2

0.7 ± 0.1

0.604

Sodium (mEq/L)

141 ± 2

141 ± 1

0.564

141 ± 2

141 ± 2

0.944

Chloride (mEq/L)

104 ± 2

103 ± 2

0.348

103 ± 2

104 ± 3

0.852

Potassium (mEq/L)

4.8 ± 0.5

4.9 ± 0.5

0.508

4.5 ± 0.5

4.4 ± 0.4

0.436

Calcium (mg/L)

9.3 ± 0.3

9.2 ± 0.4

0.238

9.3 ± 0.3

9.2 ± 0.4

0.293

Inorganic phosphorus (mg/dL)

3.4 ± 0.3

3.4 ± 0.5

0.955

3.4 ± 0.3

3.3 ± 0.5

0.386

Red blood cells (×104/μL)

439 ± 33

443 ± 32

0.643

433 ± 32

437 ± 28

0.596

White blood cells (/μL)

5493 ± 1270

5420 ± 1205

0.794

5258 ± 1362

5058 ± 1089

0.470

Platelet (×104/μL)

22.3 ± 4.4

21.9 ± 5.2

0.693

22.0 ± 4.1

21.0 ± 5.0

0.349

Hemoglobin (g/dL)

13.9 ± 0.9

13.9 ± 0.9

0.933

13.5 ± 0.9

13.5 ± 0.8

0.880

Hematocrit (%)

43.5 ± 2.7

43.6 ± 2.5

0.942

43.4 ± 2.9

43.6 ± 2.3

0.779

  1. Mean (SD); n, number of subject; P value, by unpaired t-test.
  2. 14 × 109 cells of heat-killed L. pentosus strain b240 per day for 12 weeks.
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Immunity & Ageing

ISSN: 1742-4933

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