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Table 3 IL-10 SNP (rs 1800896) genotype distribution and allele frequency from Offs, CTR and AMI

From: Pro-inflammatory genetic profile and familiarity of acute myocardial infarction

IL-10 GG (n) % GA (n) % AA (n) % G carriers (n) % A carriers (n) %
Offs (n = 154) (20) 13 (80) 51.9 (54) 35.1 (101) 65.6 (135) 87.7
CTR (n = 239) (73) 30.5 (88) 36.8 (78) 32.6 (161) 67.4 (165) 69
AMI (n = 265) (56) 21.1 (141) 53.2 (68) 25.7 (197) 74.3 (209) 78.9
Offs vs CTR χ2 = 17.378, p = 0.0001; GG carriers vs non-GG carriers: χ2 = 15.981, p = 0.0001; A carriers χ2 = 17.984. p = 0.0001
AMI vs CTR χ2 = 13.887, p = 0.001; GG carriers vs non-GG carriers: χ2 = 5.845, p = 0.016; OR = 0.609 (CI: 0.407-0.912); A carriers χ2 = 6.344, p = 0.012; OR = 1.674 (CI: 1.179-2.504)
Offs vs AMI χ2 = 6.550, p = 0.038; GG carriers vs non-GG carriers: χ2 = 4.352, p = 0.037; OR = 1.795 (CI: 1.031-3.126); AA carriers vs non-AA carriers: χ2 = 4.077, p = 0.043; OR = 0.642 (CI: 0.418-0.989); A carriers χ2 = 5.126, p = 0.024; OR = 0.525 (CI: 0.299-0.923).