Table 3 IL-10 SNP (rs 1800896) genotype distribution and allele frequency from Offs, CTR and AMI
From: Pro-inflammatory genetic profile and familiarity of acute myocardial infarction
IL-10 | GG (n) % | GA (n) % | AA (n) % | G carriers (n) % | A carriers (n) % |
|---|---|---|---|---|---|
Offs (n = 154) | (20) 13 | (80) 51.9 | (54) 35.1 | (101) 65.6 | (135) 87.7 |
CTR (n = 239) | (73) 30.5 | (88) 36.8 | (78) 32.6 | (161) 67.4 | (165) 69 |
AMI (n = 265) | (56) 21.1 | (141) 53.2 | (68) 25.7 | (197) 74.3 | (209) 78.9 |
Offs vs CTR | χ2 = 17.378, p = 0.0001; GG carriers vs non-GG carriers: χ2 = 15.981, p = 0.0001; A carriers χ2 = 17.984. p = 0.0001 | ||||
AMI vs CTR | χ2 = 13.887, p = 0.001; GG carriers vs non-GG carriers: χ2 = 5.845, p = 0.016; OR = 0.609 (CI: 0.407-0.912); A carriers χ2 = 6.344, p = 0.012; OR = 1.674 (CI: 1.179-2.504) | ||||
Offs vs AMI | χ2 = 6.550, p = 0.038; GG carriers vs non-GG carriers: χ2 = 4.352, p = 0.037; OR = 1.795 (CI: 1.031-3.126); AA carriers vs non-AA carriers: χ2 = 4.077, p = 0.043; OR = 0.642 (CI: 0.418-0.989); A carriers χ2 = 5.126, p = 0.024; OR = 0.525 (CI: 0.299-0.923). | ||||