Table 8 Cardiovascular events in Controls and Offs during a 24 years follow up.
From: Pro-inflammatory genetic profile and familiarity of acute myocardial infarction
panel A | ||||||||||
| Â | Male | Female | ||||||||
| Â | MONICA-Brianza | Offs | P | MONICA-Brianza | Offs | P | ||||
|  | Age 25-35 | (1984) | †| Age 25-35 | (1984) | †| ||||
| Â | N | % | N | % | Â | N | % | N | % | Â |
Subjects | 727 | - | 84 | - | - | 768 | - | 70 | - | - |
Ischemic heart disease* | 3 | 0.4 | 1 | 1.2 | ‡ | 2 | 0.3 | 0 | 0 | ‡ |
Stroke | 1 | 0.1 | 0 | 0 | ‡ | 0 | 0 | 0 | 0 | ‡ |
Heart disease/stroke | 4 | 0.6 | 1 | 1.2 | ‡ | 2 | 0.3 | 0 | 0 | ‡ |
Hypertension | 72 | 9.9 | 4 | 4.8 | ‡ | 63 | 8.2 | 2 | 2.9 | ‡ |
Diabetes mellitus | 2 | 0.3 | 0 | 0 | ‡ | 2 | 0.3 | 1 | 1.4 | ‡ |
Smoking | 292 | 40.2 | 29 | 34.5 | ‡ | 240 | 31.3 | 27 | 38.6 | ‡ |
panel B | ||||||||||
| Â | MONICA-Brianza | Offs | P | MONICA-Brianza | Offs | P | ||||
|  | Age 50-60 | (2008) | †| Age 50-60 | (2008) | †| ||||
| Â | N | % | N | % | Â | N | % | N | % | Â |
Subjects | 970 | - | 84 | - | - | 967 | - | 70 | - | - |
Ischemic heart disease* | 38 | 3.9 | 9 | 10.7 | 0.01 | 16 | 1.7 | 1 | 1.4 | ‡ |
Stroke | 6 | 0.6 | 4 | 4.8 | 0.01 | 3 | 0.3 | 0 | 0 | ‡ |
Heart disease/stroke | 44 | 4.5 | 13 | 15.5 | 0.0001 | 19 | 2 | 1 | 1.4 | ‡ |
Hypertension | 268 | 27.6 | 29 | 34.5 | ‡ | 350 | 36.2 | 20 | 28.6 | ‡ |
Diabetes mellitus | 39 | 4 | 8 | 9.5 | 0.05 | 30 | 3.1 | 5 | 7.1 | ‡ |
Smoking | 354 | 36.5 | 17 | 20.2 | 0.003 | 145 | 15 | 13 | 18.6 | ‡ |