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Table 2 Relationship between hematology values and age in rhesus macaques

From: Immune correlates of aging in outdoor-housed captive rhesus macaques (Macaca mulatta)

Testa Correlation coefficient (r)b P Mean values (± St. Dev.)
Younger group (2–9 years) Middle group 10–17 years Older group 18–24 years P c Units
RBC −0.1359 n.s.d 5.64 ± 0.44 5.59 ± 0.53 5.5 ± 0.61 n.s. x 106 / μL
Hgb −0.1145 n.s. 12.58 ± 0.85 12.59 ± 1.31 12.3 ± 1.3 n.s. g / dL
Hct −0.1276 n.s. 39.47 ± 3.22 39.22 ± 3.55 37.96 ± 6.48 n.s. %
MCV 0.0766 n.s. 70.01 ± 2.85 70.35 ± 3.55 70.49 ± 3.79 n.s. fL
MCH −0.0011 n.s. 22.33 ± 0.96 22.60 ± 1.61 22.28 ± 1.79 n.s. pg/cell
MCHC −0.1029 n.s. 31.89 ± 0.94 32.11 ± 1.17 31.58 ± 1.59 n.s. g / dL
RDW 0.0055 n.s. 13.49 ± 1.00 13.22 ± 2.62 13.61 ± 1.25 n.s. %
Platelets −0.1364 n.s. 4.04 ± 0.89 3.86 ± 0.93 3.69 ± 1.20 n.s. x 105 / μL
MPV 0.0613 n.s. 9.28 ± 0.92 8.90 ± 2.17 9.19 ± 1.311 n.s. fL
WBC −0.1768 0.0380 10.68 ± 5.97 9.72 ± 4.56 6.68 ± 2.94 0.0007 x 103 / μL
Lymphocytes −0.3052 0.0002 2.78 ± 1.18 2.70 ± 1.30 2.12 ± 0.66 0.0052 x 103 / μL
Monocyte −0.1989 0.0170 0.47 ± 0.24 0.42 ± 0.16 0.36 ± 0.14 0.0221 x 103 / μL
Neutrophils −0.2555 0.0020 7.07 ± 5.72 6.01 ± 4.38 4.03 ± 2.96 0.0068 x 103 / μL
Eosinophils −0.2710 0.0010 0.36 ± 0.29 0.29 ± 0.26 0.18 ± 0.15 0.0017 x 103 / μL
Basophils −0.3525 < 0.0001 0.04 ± 0.03 0.03 ± 0.03 0.02 ± 0.01 0.0004 x 103 / μL
  1. a Abbreviations of tests; RBC, red blood cells; Hgb, hemoglobin, Hct, hematocrit; MCV, mean corpuscular volume; MCH, mean corpuscular hemoglobin; MCHC, mean corpuscular hemoglobin concentration; RDW, red blood cell distribution width; MPV, mean platelet volume; WBC, white blood cells.
  2. b Pearson correlation coefficients were calculated for each hematology test over age of the rhesus macaques. P < 0.05 was considered statistically significant.
  3. c Mean values of hematology tests were calculated for all animals and within groups of rhesus macaques. Student’s t Test was measured to determine statistically significant differences between the older and younger groups of animals. P < 0.05 was considered statistically significant.
  4. d Not significant, n.s.