Immune correlates of aging in outdoor-housed captive rhesus macaques (Macaca mulatta)

Immunity & Ageing

Table 3 Relationship between blood chemistry values over age in rhesus macaques

Test	Correlation coefficient (r)^a	P	Mean values (± St. Dev.)
Test	Correlation coefficient (r)^a	P	Younger group (2–9 years)	Middle group (10–17 years)	Older group (18–24 years)	P ^b	Units
Sodium (Na)	−0.0835	n.s.^c	147.80 ± 3.23	147.04 ± 3.55	147.40 ± 3.41	n.s.	mMol/L
Potassium (K)	−0.0278	n.s.	3.86 ± 0.60	3.65 ± 0.36	3.90 ± 0.45	n.s.	mMol/L
Chloride (Cl)	0.1830	n.s.	109.00 ± 2.98	108.42 ± 5.16	110.70 ± 4.03	n.s.	mMol/L
Total protein	−0.2026	n.s.	7.01 ± 0.60	6.95 ± 0.56	6.80 ± 0.75	n.s.	g/dL
Albumin	−0.2276	0.041	3.83 ± 0.05	3.75 ± 0.50	3.60 ± 0.69	n.s.	g/dL
Globulins	0.1124	n.s.	3.18 ± 0.58	3.20 ± 0.52	3.10 ± 0.55	n.s.	g/dL
Albumin/Globulins	−0.1284	n.s.	1.26 ± 0.36	1.22 ± 0.28	1.20 ± 0.35	n.s.
Blood Urea Nitrogen (BUN)	−0.2017	n.s.	22.05 ± 9.47	21.17 ± 5.98	19.30 ± 7.33	n.s.	mg/dL
Creatinine	−0.2763	0.031	0.88 ± 0.19	0.89 ± 0.28	0.80 ± 0.32	n.s.	mg/dL
BUN/Creatinine	0.1373	n.s.	25.52 ± 8.94	24.93 ± 7.09	27.60 ± 8.89	n.s.
Glucose	0.1240	n.s.	60.72 ± 19.22	68.23 ± 22.84	64.40 ± 23.59	n.s.	mMol/L
Alanine Transaminase	−0.0125	n.s.	29.04 ± 14.66	32.35 ± 14.52	36.90 ± 18.34	n.s.	IU/L
Aspartate Transaminase	−0.3126	0.005	46.63 ± 18.38	37.88 ± 16.03	37.50 ± 18.38	0.0415	IU/l

^a Pearson correlation coefficients were calculated for each hematology test over age of the rhesus macaques. P < 0.05 was considered statistically significant.
^b Mean values of hematology tests were calculated for animals in the three age groups of rhesus macaques. Student’s t Test was measured to determine statistically significant differences between the older and younger groups of animals. P < 0.05 was considered statistically significant.
^c Not significant = n.s.

ISSN: 1742-4933