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Table 1 Main modifications of B cells and B cells products in elderly human observed in our laboratory

From: Genetics of longevity. Data from the studies on Sicilian centenarians

B cells or B cells products Changes References
Total B cells (percentage) [9]
CD19+CD5+ B1 cells (percentage and absolute number) [10]
IgG, IgA [11]
IgM, IgD [11]
IgE = [11]
Autoantibodies [12]
Naive (IgD+CD27-) [13]
DN (IgD-CD27-) [1416]