Table 2 Cellular and humoral immune modification in offspring from longevity families compared to their AM controls
From: Genetics of longevity. Data from the studies on Sicilian centenarians
T and B cell Phenotypes and Products | Changes | References |
|---|---|---|
Naïve T cells (CD3+CD8+CD45RA+CCR7+CD27+CD28+) | Increase | [8] |
Late differentiated effector memory T cells (CD3+CD8+CD45RA-CCR7-CD27-CD28-) | Decrease | [8] |
TEMRA (CD3+CD8+CD45RA+CCR7-CD27-CD28-) | Decrease | [8] |
Naïve B cells (IgD+CD27-) | Increase | [20] |
Double Negative B cells (IgG+/IgA+IgD-CD27-) | Decrease | [20] |
Serum IgM | Increase | [20] |