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Table 1 Comparison of TLR4 896 A/A and TLR4 896 AG/GG Genotype divided by Age Tertiles

From: Association of Toll-like receptor 4 polymorphism with age-dependent systolic blood pressure increase in patients with coronary artery disease

Characteristics Total cohort (n = 2679) Lower and middle age tertiles age ≥50 and <70 (n = 1772) Upper age tertile age ≥70 and <80 (n = 907)
Genotype AA AG/GG AA AG/GG AA AG/GG
Patients, n (%) 2393 (89.3) 286 (10.7) 1590 (89.7) 182 (10.3) 803 (88.6) 104 (11.4)
Age, y 65.5 ± 8.0 65.7 ± 8.0 61 ± 5.4 60.9 ± 5.5 74.6 ± 2.8# 74.4 ± 2.6#
Sex, female % 24 25 20 21 33# 33#
BMI, kg/m2 27.0 ± 3.8 27.0 ± 4.0 27.3 ± 3.8 27.5 ± 4.1 26.5 ± 3.8 26.2 ± 3.6
SBP, mmHg 150.6 ± 26.8 148.6 ± 28.2 148.2 ± 26.3 148.9 ± 26.9 154.9 ± 27.2# 148.2 ± 30.4*
DBP, mmHg 79.4 ± 4.3 79.0 ± 4.8 79.7 ± 4.2 79.2 ± 4.5 79.3 ± 4.6 78.6 ± 5.4
PP, mmHg 71.2 ± 26.3 68.8 ± 28.0 69 ± 25.9 68,5 ± 28.0 75,5 ± 26.4# 69,1 ± 29.7*
HR, bpm 73.8 ± 12.3 73.3 ± 11.7 73.4 ± 12.0 73.6 ± 11.8 74.5 ± 12.8 72.7 ± 11.5
Hypertension, % 69 64 66 66 76# 60*
Hypercholesterolemia, % 57 57 58 61 55 50
Diabetes, % 22 24 19 24 27# 24
Smoking, % 47 49 54 54 34# 40#
  1. AA versus AG/GG *P < 0.05, Lower age tertiles versus higher age tertile # P < 0.05