Table 1 Comparison of TLR4 896 A/A and TLR4 896 AG/GG Genotype divided by Age Tertiles
Characteristics | Total cohort (n = 2679) | Lower and middle age tertiles age ≥50 and <70 (n = 1772) | Upper age tertile age ≥70 and <80 (n = 907) | |||
|---|---|---|---|---|---|---|
Genotype | AA | AG/GG | AA | AG/GG | AA | AG/GG |
Patients, n (%) | 2393 (89.3) | 286 (10.7) | 1590 (89.7) | 182 (10.3) | 803 (88.6) | 104 (11.4) |
Age, y | 65.5 ± 8.0 | 65.7 ± 8.0 | 61 ± 5.4 | 60.9 ± 5.5 | 74.6 ± 2.8# | 74.4 ± 2.6# |
Sex, female % | 24 | 25 | 20 | 21 | 33# | 33# |
BMI, kg/m2 | 27.0 ± 3.8 | 27.0 ± 4.0 | 27.3 ± 3.8 | 27.5 ± 4.1 | 26.5 ± 3.8 | 26.2 ± 3.6 |
SBP, mmHg | 150.6 ± 26.8 | 148.6 ± 28.2 | 148.2 ± 26.3 | 148.9 ± 26.9 | 154.9 ± 27.2# | 148.2 ± 30.4* |
DBP, mmHg | 79.4 ± 4.3 | 79.0 ± 4.8 | 79.7 ± 4.2 | 79.2 ± 4.5 | 79.3 ± 4.6 | 78.6 ± 5.4 |
PP, mmHg | 71.2 ± 26.3 | 68.8 ± 28.0 | 69 ± 25.9 | 68,5 ± 28.0 | 75,5 ± 26.4# | 69,1 ± 29.7* |
HR, bpm | 73.8 ± 12.3 | 73.3 ± 11.7 | 73.4 ± 12.0 | 73.6 ± 11.8 | 74.5 ± 12.8 | 72.7 ± 11.5 |
Hypertension, % | 69 | 64 | 66 | 66 | 76# | 60* |
Hypercholesterolemia, % | 57 | 57 | 58 | 61 | 55 | 50 |
Diabetes, % | 22 | 24 | 19 | 24 | 27# | 24 |
Smoking, % | 47 | 49 | 54 | 54 | 34# | 40# |