|
Characteristics
|
Total cohort (n = 2679)
|
Lower and middle age tertiles age ≥50 and <70 (n = 1772)
|
Upper age tertile age ≥70 and <80 (n = 907)
|
|---|
|
Genotype
|
AA
|
AG/GG
|
AA
|
AG/GG
|
AA
|
AG/GG
|
|
Patients, n (%)
|
2393 (89.3)
|
286 (10.7)
|
1590 (89.7)
|
182 (10.3)
|
803 (88.6)
|
104 (11.4)
|
|
Age, y
|
65.5 ± 8.0
|
65.7 ± 8.0
|
61 ± 5.4
|
60.9 ± 5.5
|
74.6 ± 2.8#
|
74.4 ± 2.6#
|
|
Sex, female %
|
24
|
25
|
20
|
21
|
33#
|
33#
|
|
BMI, kg/m2
|
27.0 ± 3.8
|
27.0 ± 4.0
|
27.3 ± 3.8
|
27.5 ± 4.1
|
26.5 ± 3.8
|
26.2 ± 3.6
|
|
SBP, mmHg
|
150.6 ± 26.8
|
148.6 ± 28.2
|
148.2 ± 26.3
|
148.9 ± 26.9
|
154.9 ± 27.2#
|
148.2 ± 30.4*
|
|
DBP, mmHg
|
79.4 ± 4.3
|
79.0 ± 4.8
|
79.7 ± 4.2
|
79.2 ± 4.5
|
79.3 ± 4.6
|
78.6 ± 5.4
|
|
PP, mmHg
|
71.2 ± 26.3
|
68.8 ± 28.0
|
69 ± 25.9
|
68,5 ± 28.0
|
75,5 ± 26.4#
|
69,1 ± 29.7*
|
|
HR, bpm
|
73.8 ± 12.3
|
73.3 ± 11.7
|
73.4 ± 12.0
|
73.6 ± 11.8
|
74.5 ± 12.8
|
72.7 ± 11.5
|
|
Hypertension, %
|
69
|
64
|
66
|
66
|
76#
|
60*
|
|
Hypercholesterolemia, %
|
57
|
57
|
58
|
61
|
55
|
50
|
|
Diabetes, %
|
22
|
24
|
19
|
24
|
27#
|
24
|
|
Smoking, %
|
47
|
49
|
54
|
54
|
34#
|
40#
|
- AA versus AG/GG *P < 0.05, Lower age tertiles versus higher age tertile #
P < 0.05
