Association of Toll-like receptor 4 polymorphism with age-dependent systolic blood pressure increase in patients with coronary artery disease

Table 2 Univariate analysis for systolic blood pressure of the whole cohort and devided by tertiles

A: Whole cohort Parameter
	Coefficient B	SEM	Beta	P
Age, y	0.509	0.064	0.151	<0.001
Sex (M = 0,F = 1)	10.943	1.197	0.174	<0.001
BMI, kg/m²	0.05	0.138	0.007	0.7
Diabetes (No = 0, Yes = 1)	3.445	1.256	0.053	0.006
Hypercholesterolemia (No = 0, Yes = 1)	2.987	1.053	0.055	0.005
TLR4 SNP 896 (AA = 0, AG/GG = 1)	−1.595	1.712	−0.018	0.35
B: Lower and middle age tertiles (age ≥50 and <70)
Parameter	Coefficient B	SEM	Beta	P
Age, y	0.719	0.114	0.149	<0.001
Sex (M = 0,F = 1)	11.624	1.550	0.176	<0.001
BMI, kg/m²	0.274	0.166	0.04	0.1
Diabetes (No = 0, Yes = 1)	5.755	1.577	0.087	<0.001
Hypercholesterolemia (No = 0, Yes = 1)	2.416	1.273	0.045	0.058
TLR4 SNP 896 (AA = 0, AG = 1)	1.211	2.092	0.014	0.56
C: Upper age tertile (age ≥70 and <80)
Parameter	Coefficient B	SEM	Beta	P
Age, y	0.492	0.324	0.051	0.13
Sex (M = 0,F = 1)	8.324	1.938	0.142	<0.001
BMI, kg/m²	−0.148	0.246	−0.021	0.54
Diabetes (No = 0, Yes = 1)	−1509	2.075	−0.024	0.46
Hypercholesterolemia (No = 0, Yes = 1)	4.716	1.845	0.085	0.011
TLR4 SNP 896 (AA = 0, AG/GG = 1)	−7.023	2.931	−0.08	0.017

ISSN: 1742-4933