A: Whole cohort Parameter | ||||
---|---|---|---|---|
Coefficient B | SEM | Beta | P | |
Age, y | 0.509 | 0.064 | 0.151 | <0.001 |
Sex (M = 0,F = 1) | 10.943 | 1.197 | 0.174 | <0.001 |
BMI, kg/m2 | 0.05 | 0.138 | 0.007 | 0.7 |
Diabetes (No = 0, Yes = 1) | 3.445 | 1.256 | 0.053 | 0.006 |
Hypercholesterolemia (No = 0, Yes = 1) | 2.987 | 1.053 | 0.055 | 0.005 |
TLR4 SNP 896 (AA = 0, AG/GG = 1) | −1.595 | 1.712 | −0.018 | 0.35 |
B: Lower and middle age tertiles (age ≥50 and <70) | ||||
Parameter | Coefficient B | SEM | Beta | P |
Age, y | 0.719 | 0.114 | 0.149 | <0.001 |
Sex (M = 0,F = 1) | 11.624 | 1.550 | 0.176 | <0.001 |
BMI, kg/m2 | 0.274 | 0.166 | 0.04 | 0.1 |
Diabetes (No = 0, Yes = 1) | 5.755 | 1.577 | 0.087 | <0.001 |
Hypercholesterolemia (No = 0, Yes = 1) | 2.416 | 1.273 | 0.045 | 0.058 |
TLR4 SNP 896 (AA = 0, AG = 1) | 1.211 | 2.092 | 0.014 | 0.56 |
C: Upper age tertile (age ≥70 and <80) | ||||
Parameter | Coefficient B | SEM | Beta | P |
Age, y | 0.492 | 0.324 | 0.051 | 0.13 |
Sex (M = 0,F = 1) | 8.324 | 1.938 | 0.142 | <0.001 |
BMI, kg/m2 | −0.148 | 0.246 | −0.021 | 0.54 |
Diabetes (No = 0, Yes = 1) | −1509 | 2.075 | −0.024 | 0.46 |
Hypercholesterolemia (No = 0, Yes = 1) | 4.716 | 1.845 | 0.085 | 0.011 |
TLR4 SNP 896 (AA = 0, AG/GG = 1) | −7.023 | 2.931 | −0.08 | 0.017 |