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Table 1 Clinical characteristics (means ± SD) of the study population at the age of 50 years

From: NLR family pyrin domain containing 3 (NLRP3) inflammasome gene polymorphism rs7512998 (C>T) predicts aging-related increase of blood pressure, the TAMRISK study

  Cases (n = 325) Controls (n = 444) P
Age (years) 50 ± 0 50 ± 0  
Gender (male) % 59 63 0.279
Blood pressure medication (%) 73 0 <0.000
Smoking (%) 27 25 0.588
Body mass index (kg/m2) 28.8 ± 5.1 25.5 ± 3.6 <0.000
Cholesterol (mmol/l) 5.40 ± 0.98 5.37 ± 0.88 0.789
Glucose (mmol/l) 5.17 ± 1.30 4.86 ± 0.54 <0.000
Systolic blood pressure (mm Hg) 142.7 ± 16.7 129.3 ± 14.8 <0.000
Diastolic blood pressure (mm Hg) 92.8 ± 8.9 84.4 ± 9.1 <0.000
NLRP3 gene polymorphism rs7512998 (CC/TC/TT) % 1.5/28.9/69.6 2.5/27.8/69.7 0.647
rs7512998 (CC+TC/TT) % 30.4/69.6 30.3/69.7 0.626