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Table 2 Clinical characteristics (means ± SD) of the study population stratified according to NLRP3 gene polymorphism rs7512998. P values <0.05 are in bold

From: NLR family pyrin domain containing 3 (NLRP3) inflammasome gene polymorphism rs7512998 (C>T) predicts aging-related increase of blood pressure, the TAMRISK study

  CC + TC TT p
N at 50 (%) 232 (30) 537 (70)  
Hypertension (%) 41.2 42.3 0.807
Blood pressure medication (%) 28.1 32.2 0.273
Smoking (%) 23 28 0.128
Systolic blood pressure (mmHg) 137.6 (18.0) 134.0 (16.2) 0.006
Diastolic blood pressure (mmHg) 89.3 (10.2) 87.4 (9.6) 0.011
Body mass index (kg/m2) 27.3 (4.8) 26.8 (4.6) 0.196
Cholesterol (mmol/l) 5.4 (0.9) 5.4 (1.0) 0.959
Glucose (mmol/l) 5.0 (0.6) 5.1 (1.3) 0.309
N at 45 (%) 199 (29) 479 (71)  
Hypertension (%) 12.6 16.2 0.253
Blood pressure medication (%) 7.6 12.4 0.083
Smoking (%) 42 42 0.911
Systolic blood pressure (mmHg) 133.3 (16.1) 132.4 (13.6) 0.417
Diastolic blood pressure (mmHg) 85.3 (9.5) 85.2 (9.2) 0.906
Body mass index (kg/m2) 26.7 (4.1) 26.3 (4.3) 0.219
Cholesterol (mmol/l) 5.5 (1.1) 5.5 (1.1) 0.617
Glucose (mmol/l) 5.4 (0.8) 5.2 (0.9) 0.449