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Table 2 Clinical characteristics (means ± SD) of the study population stratified according to NLRP3 gene polymorphism rs7512998. P values <0.05 are in bold

From: NLR family pyrin domain containing 3 (NLRP3) inflammasome gene polymorphism rs7512998 (C>T) predicts aging-related increase of blood pressure, the TAMRISK study

 

CC + TC

TT

p

N at 50 (%)

232 (30)

537 (70)

 

Hypertension (%)

41.2

42.3

0.807

Blood pressure medication (%)

28.1

32.2

0.273

Smoking (%)

23

28

0.128

Systolic blood pressure (mmHg)

137.6 (18.0)

134.0 (16.2)

0.006

Diastolic blood pressure (mmHg)

89.3 (10.2)

87.4 (9.6)

0.011

Body mass index (kg/m2)

27.3 (4.8)

26.8 (4.6)

0.196

Cholesterol (mmol/l)

5.4 (0.9)

5.4 (1.0)

0.959

Glucose (mmol/l)

5.0 (0.6)

5.1 (1.3)

0.309

N at 45 (%)

199 (29)

479 (71)

 

Hypertension (%)

12.6

16.2

0.253

Blood pressure medication (%)

7.6

12.4

0.083

Smoking (%)

42

42

0.911

Systolic blood pressure (mmHg)

133.3 (16.1)

132.4 (13.6)

0.417

Diastolic blood pressure (mmHg)

85.3 (9.5)

85.2 (9.2)

0.906

Body mass index (kg/m2)

26.7 (4.1)

26.3 (4.3)

0.219

Cholesterol (mmol/l)

5.5 (1.1)

5.5 (1.1)

0.617

Glucose (mmol/l)

5.4 (0.8)

5.2 (0.9)

0.449