IL7R gene expression network associates with human healthy ageing

Immunity & Ageing

Table 3 Gene expression of offspring from nonagenarians compared to controls by linear regression analysis

Gene	Coef	FC	P	Bonferroni
*IL7R*	−0.18	0.89	0.001	0.006
IL2RG	−0.72	0.61	0.563	1.000
IL7	−0.39	0.77	0.050	0.350
TSLP	−0.01	0.99	0.140	0.980
CRLF2	−0.04	0.97	0.742	1.000
JAK1	0.08	1.05	0.557	1.000
JAK3	−0.30	0.81	0.650	1.000

Genes significantly differentially expressed with at least 5 % are depicted in bold
Coef coefficient from linear regression model, FC fold change (above one indicates a higher expression in offspring from long-lived individuals), P raw P-value from the linear regression model, Bonferroni P-value after adjustment for multiple testing (N = 7) by the Bonferroni method

ISSN: 1742-4933