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Table 2 Effect of probiotic (B. subtilis CU1) and placebo consumption on clinical outcomes of infectious diseases

From: Probiotic strain Bacillus subtilis CU1 stimulates immune system of elderly during common infectious disease period: a randomized, double-blind placebo-controlled study

 

Whole population (N = 100)

Subset of population (N = 44)

 

Probiotic group (N = 50)

Placebo group (N = 50)

P

Probiotic group (N = 22)

Placebo group (N = 22)

P

 

Mean

SD

Mean

SD

Mean

SD

Mean

SD

Mean number of days with CID

5.1

7.0

6.6

7.3

0.2015a

4.5

7.3

7.3

8.2

0.1101a

Mean duration of CID (d)

5.0

4.6

5.3

4.1

0.2361a

5.8

5.6

5.7

4.1

0.2361a

Mean intensity of CID

8.1

5.0

7.6

4.4

0.7400a

9.0

6.2

8.8

5.3

0.7400a

CID frequency

1.0

1.2

1.2

1.2

0.3290a

0.8

1.0

1.3

1.2

0.1117a

Subjects with at least one CID

    

0.4106b

    

0.1260b

n

29

33

 

11

16

 

 %

58 · 0

66 · 0

 

50 · 0

72 · 7

 

Mean number of days with RI

4.4

6.9

6.2

7.2

0.1027a

3.7

6.9

6.6

7.9

0.0818a

Mean duration of RI (d)

5.9

5.0

5.6

4.2

0.9043a

6.8

6.3

6.1

4.3

0.9325a

Mean intensity of RI

9.3

5.3

7.8

4.6

0.1428a

11.1

6.3

9.3

5.6

0.3473a

RI frequency

0.7

0.9

1.1

1.2

0.1181a

0.6

0.7

1.1

0.9

0.0323 a

Subjects with at least one RI

    

0.1609b

    

0.0701b

n

24

31

 

10

16

 

 %

48.0

62.0

 

45.5

72.7

 
  1. Data are presented for the whole population (N = 100) and the subset of population with biology analysis (N = 44). (Mean values and standard deviations; numbers and percentages)
  2. Statistical differences were evaluated using Wilcoxon-Mann-Whitney’s test or Savage’s test according to the asymmetry of data (a), or logistic regression model (b)