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Table 4 TLR-6 P249S is associated with healthy aging in non-smokers

From: TLR-6 SNP P249S is associated with healthy aging in nonsmoking Eastern European Caucasians - A cohort study

Disease Variant P-value OR (95 % CI)
All subjects
Combined aging related diseases P/P - -
P/S 0.281 0.876 (0.689–1.114)
S/S 0.273 0.825 (0.585–1.163)
P/S + S/S 0.208 0.864 (0.689–1.085)
Non smokers    
Combined aging related diseases P/P - -
P/S 0.024 0.682 (0.489–0.951)
S/S 0.018 0.566 (0.353–0.909)
P/S + S/S 0.008 0.654 (0.477–0.897)
  1. P-values and OR were determined by logistic regression using the wild type genotype as reference, and micro-inflammation (IL-6 level), age and BMI as co-factors. Subjects with a white blood cell count above 10.000/μl were excluded