Table 5 TLR-6 P249S is associated with CVD and DMT 2 in non-smokers
Disease | Variant | P-value | OR (95 % CI) |
|---|---|---|---|
All subjects | |||
CVD | P/P | - | - |
P/S | 0.188 | 0.770 (0.522–1.136) | |
S/S | 0.018 | 0.483 (0.265–0.882) | |
P/S + S/S | 0.061 | 0.702 (0.484–1.017) | |
Cancer | P/P | - | - |
P/S | 0.416 | 0.745 (0.367–1.513) | |
S/S | 0.353 | 0.602 (0.207–1.756) | |
P/S + S/S | 0.318 | 0.710 (0.363–1.390) | |
Lung disease | P/P | - | - |
P/S | 0.216 | 0.732 (0.446–1.201) | |
S/S | 0.509 | 0.793 (0.399–1.577) | |
P/S + S/S | 0.219 | 0.746 (0.467–1.191) | |
DMT 2 | P/P | - | - |
P/S | 0.007 | 0.443 (0.244–0.804) | |
S/S | 0.230 | 0.617 (0.281–1.356) | |
P/S + S/S | 0.010 | 0.486 (0.281–0.839) | |
Cognitive impairment | P/P | - | - |
P/S | 0.284 | 0.794 (0.522–1.210) | |
S/S | 0.345 | 0.751 (0.415–1.360) | |
P/S + S/S | 0.232 | 0.784 (0.526–1.1168) | |
Combined aging related diseases, CVD excluded | P/P | - | - |
P/S | 0.016 | 0.628 (0.431–0.915) | |
S/S | 0.116 | 0.656 (0.388–1.109) | |
P/S + S/S | 0.012 | 0.635 (0.445–0.906) |