Fig. 3
From: pERK-dependent defective TCR-mediated activation of CD4+ T cells in end-stage renal disease patients
Phosphorylation of p38 in T cells subsets from healthy individuals (HI) and end stage renal disease (ESRD) patients. Phosphorylation of p38 in (a) CD4+, (b) CD4+ naive, (c) CD4+ central memory (CM), (d) CD4+ effector memory (EM), as well as (e) CD8+, (f) CD8+ naive, (g) CD8+ CM, (h) CD8+EM, (i) CD8+ highly differentiated effector T cells (EMRA). Dots and squares represent young (n = 13) and elderly HI (n = 11), and upward- and downward-facing triangles correspond to young (n = 12) and elderly (n = 12) patients, respectively. P value: *< 0.05; Data are given as median with interquartile range