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Table 2 Total symptom score and clinical evaluation score (panel A), and rhinomanometry measurements (panel B) of patients with chronic rhinitis, pharyngitis or sinusitis at admission (T0), after nasal inhalations with thermal water (T1) and at phone follow up 1 year later (T2)

From: Gene and protein expression of CXCR4 in adult and elderly patients with chronic rhinitis, pharyngitis or sinusitis undergoing thermal water nasal inhalations

A) Total symptom scores in T0 - T1 - T2, and clinical examination scores in T0 – T1
  T0 Mean ± SD
(range)
N = 183
T1 Mean ± SD
(range)
N = 165
T2 Mean ± SD (range)
N = 74
P - valuea
(T0 vs. T1)
P - valuea
(T0 vs. T2)
Total symptom score (TSS) 5.7 ± 3.3
(0–18)
2.7 ± 2.3
(0–12)
2.3 ± 2.6
(0–12)
< 0.00001 < 0.00001
Clinical examination score (CES) 1.4 ± 1.2
(0–5)
0.6 ± 0.7
(0–4)
n.a. < 0.0001 n.a.
B) Rhinomanometry measurements in T0 - T1
  Inhalation resistance (Pa/ml s) Exhalation resistance (Pa/ml s)
  N T0
Mean ± SD
T1
Mean ± SD
P - valueb N T0
Mean ± SD
T1
Mean ± SD
P - valueb
All patients 105 0.40 ± 0.35 0.51 ± 0.61 NS 103 0.40 ± 0.35 0.53 ± 0.60 =0.01
Pathologyc
J30-J31.0 Rhinitis 28 0.40 ± 0.38 0.63 ± 1.00 NS 28 0.40 ± 0.32 0.67 ± 0.96 NS
J31.1-J31.2 Pharyngitis 24 0.43 ± 0.43 0.44 ± 0.37 NS 24 0.46 ± 0.41 0.45 ± 0.26 NS
J32 Sinusitis 57 0.38 ± 0.28 0.49 ± 0.44 NS 55 0.36 ± 0.31 0.49 ± 0.43 =0.009
Cigarette smoke
Never smokers 47 0.39 ± 0.32 0.44 ± 0.38 NS 49 0.39 ± 0.34 0.46 ± 0.38 NS
Former smokers 46 0.39 ± 0.34 0.53 ± 0.11 NS 41 0.37 ± 0.33 0.60 ± 0.74 NS
Currentsmokers 12 0.52 ± 0.45 0.69 ± 0.84 NS 13 0.48 ± 0.40 0.62 ± 0.81 NS
  1. n.a. not assessed, SD standard deviation, NS not statistically significant (p > 0.05), SD standard deviation
  2. aWilcoxon signed rank sum test
  3. bWilcoxon signed rank sum test T0 vs. T1
  4. cFigures do not add up because 10 patients declared two pathologies simultaneously