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Table 4 CXCR4 protein and gene expression in patients undergoing thermal water nasal inhalation

From: Gene and protein expression of CXCR4 in adult and elderly patients with chronic rhinitis, pharyngitis or sinusitis undergoing thermal water nasal inhalations

 

CXCR4 protein expression

CXCR4 gene expression

 

N

T0

Mean ± SD

T1

Mean ± SD

P - valuea

N

T0

Mean ± SD

T1

Mean ± SD

P - valuea

Controls

10

0.97 ± 0.51

 

NSb

10

0.66 ± 0.44

–

= 0.025b

All patients

40

1.0 ± 0.39

2.6 ± 0.66

< 0.0001d

143

1.2 ± 0.68

3.3 ± 1.2

< 0.0001d

Pathologyc

 J30-J31.0 Rhinitis

10

1.2 ± 0.37

2.4 ± 0.66

< 0.0001d

34

1.1 ± 0.6

3.5 ± 1.2

< 0.0001d

 J31.1-J31.2 Pharyngitis

7

1.2 ± 0.45

2.7 ± 0.6

= 0.0001d

37

1.2 ± 0.59

3.1 ± 1.3

= 0.0001d

 J32 Sinusitis

24

0.96 ± 0.37

2.6 ± 0.69

< 0.0001d

77

1.1 ± 0.77

3.3 ± 1.1

< 0.0001d

Cigarette smoke

 Never smokers

23

0.99 ± 0.39

2.6 ± 0.66

< 0.0001d

68

1.2 ± 0.66

3.5 ± 1.2

< 0.0001d

 Former smokers

13

1.0 ± 0.36

2.6 ± 0.50

< 0.0001d

56

1.1 ± 0.57

3.3 ± 1.2

< 0.0001d

 Current smokers

4

1.4 ± 0.38

2.4 ± 1.2

NS

19

1.1 ± 0.98

2.7 ± 0.93

< 0.0001d

  1. NS not statistically significant (p > 0.05), SD standard deviation
  2. aFisher’s exact Test for difference T0 vs. T1
  3. bDifference controls vs. T0
  4. cFigures do not add up because some patients declared two pathologies simultaneously
  5. dDifference statistically significant after Bonferroni adjustment for multiple comparisons (cut-off is ≈ 0.005)
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Immunity & Ageing

ISSN: 1742-4933

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