Skip to main content

Table 4 CXCR4 protein and gene expression in patients undergoing thermal water nasal inhalation

From: Gene and protein expression of CXCR4 in adult and elderly patients with chronic rhinitis, pharyngitis or sinusitis undergoing thermal water nasal inhalations

  CXCR4 protein expression CXCR4 gene expression
  N T0
Mean ± SD
T1
Mean ± SD
P - valuea N T0
Mean ± SD
T1
Mean ± SD
P - valuea
Controls 10 0.97 ± 0.51   NSb 10 0.66 ± 0.44 = 0.025b
All patients 40 1.0 ± 0.39 2.6 ± 0.66 < 0.0001d 143 1.2 ± 0.68 3.3 ± 1.2 < 0.0001d
Pathologyc
J30-J31.0 Rhinitis 10 1.2 ± 0.37 2.4 ± 0.66 < 0.0001d 34 1.1 ± 0.6 3.5 ± 1.2 < 0.0001d
J31.1-J31.2 Pharyngitis 7 1.2 ± 0.45 2.7 ± 0.6 = 0.0001d 37 1.2 ± 0.59 3.1 ± 1.3 = 0.0001d
J32 Sinusitis 24 0.96 ± 0.37 2.6 ± 0.69 < 0.0001d 77 1.1 ± 0.77 3.3 ± 1.1 < 0.0001d
Cigarette smoke
Never smokers 23 0.99 ± 0.39 2.6 ± 0.66 < 0.0001d 68 1.2 ± 0.66 3.5 ± 1.2 < 0.0001d
Former smokers 13 1.0 ± 0.36 2.6 ± 0.50 < 0.0001d 56 1.1 ± 0.57 3.3 ± 1.2 < 0.0001d
Current smokers 4 1.4 ± 0.38 2.4 ± 1.2 NS 19 1.1 ± 0.98 2.7 ± 0.93 < 0.0001d
  1. NS not statistically significant (p > 0.05), SD standard deviation
  2. aFisher’s exact Test for difference T0 vs. T1
  3. bDifference controls vs. T0
  4. cFigures do not add up because some patients declared two pathologies simultaneously
  5. dDifference statistically significant after Bonferroni adjustment for multiple comparisons (cut-off is ≈ 0.005)