Fig. 3

Expression of SOD2 and surface HSP70 in non-stimulated and stimulated NK cells of the young, the old aged under 85 and the oldest seniors (aged over 85). Data are presented as means ± SEM and concern expression of the studied proteins in NK cells demonstrated as percentages of cells with expression of a particular protein (%) or mean fluorescence intensity (MFI). The same symbols over bars ^X, ^<, ^●, ^T, ^o, ^V, ^, ^Δ, ^Y denote statistically significant differences between similarly treated NK cells of different age groups (i.e. young vs old; young vs oldest or old vs oldest). Horizontal lines above paired bars denote statistically significant differences between treated and untreated NK cells of the same age group (i.e. non-stimulated vs stimulated with IL-2, LPS or PMA with ionomycin). a Expression of SOD2 (%): ^Δp < 0.001; ^, ^Yp < 0.01. b Expression of SOD2 (MFI): ^T, ^, ^Vp < 0.01; ^Δ, ^● p < 0.05. c Expression of HSP70^surface (%): ^X, ^o, ^Δp < 0.001; ^T, ^<, ^V, ^● p < 0.01. d Expression of HSP70^surface (MFI): ^Δp ≤ 0.001