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Table 1 Characteristics of the study population

From: NK cells of the oldest seniors represent constant and resistant to stimulation high expression of cellular protective proteins SIRT1 and HSP70

Parameter

Young

Old

Oldest

Number

31

30

25

Age (yr)

20.9 ± 0.3

75.6 ± 0.9

88.5 ± 0.5

Sex (F/M)

22/9

20/10

20/5

Smoking status

 Current smoker

6

3

1

 Ex-smoker

3

3

0

 Nonsmoker

22

24

24

Weight (kg)

59.8 ± 1.7a,b

68.7 ± 2.0a

68.4 ± 2.3b

BMI (Body Mass Index)

20.4 ± 0.4a,b

25.6 ± 0.6a

26.5 ± 0.9b

Total cholesterol (mg/dL)

170.5 ± 5.6a

193.6 ± 8.3a

184.1 ± 9.4

HDL – cholesterol (mg/dL)

58.7 ± 2.6a,b

47.3 ± 2.3a

43.7 ± 2.2b

LDL – cholesterol (mg/dL)

96.1 ± 4.3a

123.3 ± 7.3a

113.7 ± 6.9

Triglyceride (mg/dL)

78.3 ± 8.2a,b

114.8 ± 11.2a

133.0 ± 14.8b

Glucose (mg/dL)

89.35 ± 1.33

94.4 ± 3.3

91.36 ± 3.4

Creatinine (mg/dL)

0.86 ± 0.03b

0.87 ± 0.04c

1.05 ± 0.05b c

Uric acid (mg/dL)

4.95 ± 0.21b

5.37 ± 0.28

6.22 ± 0.36b

  1. All data are presented as means ± SEM. Statistically significant differences between age groups are marked with:
  2. ayoung vs old
  3. byoung vs oldest
  4. cold vs oldest