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Table 3 CFR at baseline (Time 0) and after 4 weeks of daily NUT combination intake (t-test for paired data)

From: Different age-independent effects of nutraceutical combinations on endothelium-mediated coronary flow reserve

Combination A

Time 0

(n = 14)

4 weeks CPT CFR

(n = 14)

p value

Resting Systolic BP (mmHg)

124.6 ± 6.3

125.7 ± 8.9

0.865

 Diastolic BP (mmHg)

79.3 ± 6.5

80.7 ± 8.0

0.391

 Heart rate (bpm)

66.1 ± 13.1

71.2 ± 10.8

0.297

 Coronary flow velocity (cm/s)

20.8 ± 4.0

20.4 ± 3.9

0.542

Post CPT Systolic BP (mmHg)

121.7 ± 15.8

125.7 ± 11.6

0.474

 Diastolic BP (mmHg)

73.1 ± 9.1

75.5 ± 8.4

0.476

 Heart rate (bpm)

69.5 ± 15.0

69.9 ± 7.7

0.521

 Coronary flow velocity (cm/s)

28.9 ± 6.2

31.9 ± 6.2

0.007

CPT-derived CFR

1.39 ± 0.17

1.59 ± 0.14

< 0.0001

Combination B

Time 0

(n = 13)

4-weeks CPT CFR

(n = 13)

p value

Resting Systolic BP (mmHg)

133.9 ± 7.8

131.2 ± 9.6

0.269

 Diastolic BP (mmHg)

80.6 ± 9.5

79.4 ± 9.7

0.862

 Heart rate (bpm)

69.9 ± 10.8

67.3 ± 6.1

0.351

 Coronary flow velocity (cm/s)

19.3 ± 4.5

19.2 ± 3.7

0.820

Post CPT Systolic BP (mmHg)

120.8 ± 12.9

123.3 ± 14.9

0.600

 Diastolic BP (mmHg)

75.7 ± 7.6

78.3 ± 10.9

0.417

 Heart rate (bpm)

69.3 ± 10.1

70.3 ± 7.3

0.531

 Coronary flow velocity (cm/s)

27.5 ± 5.2

28.3 ± 5.1

0.435

CPT-derived CFR

1.43 ± 0.12

1.48 ± 0.17

0.323

  1. BP Blood pressure, CFR Coronary flow reserve, CPT Cold Pressure Test. Boldface= statistically significant p value