Combination A | Time 0 (n = 14) | 4 weeks CPT CFR (n = 14) | p value |
Resting Systolic BP (mmHg) | 124.6 ± 6.3 | 125.7 ± 8.9 | 0.865 |
Diastolic BP (mmHg) | 79.3 ± 6.5 | 80.7 ± 8.0 | 0.391 |
Heart rate (bpm) | 66.1 ± 13.1 | 71.2 ± 10.8 | 0.297 |
Coronary flow velocity (cm/s) | 20.8 ± 4.0 | 20.4 ± 3.9 | 0.542 |
Post CPT Systolic BP (mmHg) | 121.7 ± 15.8 | 125.7 ± 11.6 | 0.474 |
Diastolic BP (mmHg) | 73.1 ± 9.1 | 75.5 ± 8.4 | 0.476 |
Heart rate (bpm) | 69.5 ± 15.0 | 69.9 ± 7.7 | 0.521 |
Coronary flow velocity (cm/s) | 28.9 ± 6.2 | 31.9 ± 6.2 | 0.007 |
CPT-derived CFR | 1.39 ± 0.17 | 1.59 ± 0.14 | < 0.0001 |
Combination B | Time 0 (n = 13) | 4-weeks CPT CFR (n = 13) | p value |
Resting Systolic BP (mmHg) | 133.9 ± 7.8 | 131.2 ± 9.6 | 0.269 |
Diastolic BP (mmHg) | 80.6 ± 9.5 | 79.4 ± 9.7 | 0.862 |
Heart rate (bpm) | 69.9 ± 10.8 | 67.3 ± 6.1 | 0.351 |
Coronary flow velocity (cm/s) | 19.3 ± 4.5 | 19.2 ± 3.7 | 0.820 |
Post CPT Systolic BP (mmHg) | 120.8 ± 12.9 | 123.3 ± 14.9 | 0.600 |
Diastolic BP (mmHg) | 75.7 ± 7.6 | 78.3 ± 10.9 | 0.417 |
Heart rate (bpm) | 69.3 ± 10.1 | 70.3 ± 7.3 | 0.531 |
Coronary flow velocity (cm/s) | 27.5 ± 5.2 | 28.3 ± 5.1 | 0.435 |
CPT-derived CFR | 1.43 ± 0.12 | 1.48 ± 0.17 | 0.323 |