Fig. 4

B lymphocyte amounts in the blood of 3-, 10-month-old male and female APOE3- and APOE4-TR mice. a Representative CD19+ B cell analysis diagram by flow cytometry in blood of different groups. b The percentages of CD19 + B cell in blood of different groups. Data were expressed as mean ± SEM and were analyzed by ANOVA followed by Bonferroni post-test, Asterisks (*) and pound signs (#) indicate significant difference to 10-month-old female APOE3-TR and 3-month-old female APOE4-TR control mice as indicated, respectively. **P < 0.01, #P < 0.05, n = 4–6