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Fig. 6 | Immunity & Ageing

Fig. 6

From: Akkermansia muciniphila ameliorates the age-related decline in colonic mucus thickness and attenuates immune activation in accelerated aging Ercc1−/Δ7 mice

Fig. 6

Distribution of B cell subtypes in spleen and bone marrow (BM) after supplementation with Akkermansia muciniphila. a Mean frequencies of CD19+CD3 B cells in spleen. b Flow cytometric analysis of live single CD19+CD3 cells in spleen. c Mean frequencies of CD5+CD43+ B1 cells in spleen. d Mean frequencies of B cells in BM. e Flow cytometric analysis of live single CD19+ cells, divided in pro-B cells, large cycling pre-B cells and small resting pre-B cells in BM. f Mean frequencies Mature B cells, g Immature B cells, h Pro-B cells, i Small resting pre-B cells and (j) Large cycling pre-B cells in BM. Data represent the mean + SEM from four to six mice per group. *p < 0.05

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