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Fig. 3 | Immunity & Ageing

Fig. 3

From: RVG-modified exosomes derived from mesenchymal stem cells rescue memory deficits by regulating inflammatory responses in a mouse model of Alzheimer’s disease

Fig. 3

Targeted exosomes derived from MSCs repressed activation of astrocytes after injection intravenously. (a) Representative immunofluorescence images of GFAP protein expression in each group. (b) Quantification of the mean density of GFAP. The AD mice treated with MSC-RVG-Exo showed the lowest level of GFAP expression among the groups. Scale bar = 25 μm. *P < 0.05 and **P < 0.01 versus the AD group. ##P < 0.01 versus the MSC-Exo group, by one-way ANOVA; n = 5

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