Fig. 2

Maturational subsets of CD4⁺ and CD8⁺ T-cells expressing Ki67⁺. a-d Frequencies of CD4⁺ maturational subsets expressing the proliferation marker Ki67⁺. e-h Frequencies of CD8⁺ maturational subsets expressing the proliferation marker Ki67⁺. Comparisons between the groups of vaccine non-responders (n = 33) and responders (n = 27) were made using the nonparametric Mann–Whitney U test. Variables with a p value < 0.05 were considered statistically significant and are shown in bold. *After correction for multiple comparisons by the Benjamini-Hochberg procedure, applying a 10% FDR, all statistical significances remained. Note: CM, central memory; EM, effector memory; and TemRA, terminally differentiated effector memory