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Table 7 Partial correlations of inflammatory markers with bone health indicators adjusting for age and BMI

From: Inflammatory markers and bone health in postmenopausal women: a cross-sectional overview

  Spine BMD Spine T-score Hip BMD Hip T-score P1NP (ug/L) CTX-1 (ug/L) PTH (pmol/L) 25(OH)D3 (nmol/L)
IL-1β (pg/ml) −0.188 − 0.197 − 0.217 − 0.188 0.010 −0.064 − 0.039 0.092
IFN-α2 (pg/ml) −0.003 − 0.017 − 0.075 − 0.087 − 0.185 − 0.222* 0.065 0.054
IFN-γ (pg/ml) 0.020 0.008 −0.103 − 0.101 − 0.145 −0.221* 0.028 0.174
TNF-α (pg/ml) 0.183 0.180 0.102 0.092 −0.009 − 0.012 0.064 − 0.079
MCP-1 (pg/ml) 0.084 0.067 0.024 0.027 −0.086 − 0.154 0.037 0.277**
IL-6 (pg/ml) −0.105 −0.131 − 0.256* − 0.266* − 0.222* − 0.166 − 0.107 0.228*
IL-8 (pg/ml) 0.015 0.005 −0.093 −0.087 0.004 −0.081 − 0.093 0.190
IL-10 (pg/ml) −0.100 −0.108 − 0.160 − 0.174 − 0.069 − 0.163 − 0.115 0.190
IL-12p70 (pg/ml) −0.094 − 0.102 − 0.185 − 0.202 − 0.156 − 0.228* − 0.128 0.158
IL-17A (pg/ml) −0.057 − 0.067 − 0.049 − 0.011 − 0.062 −0.123 − 0.167 0.240*
IL-18 (pg/ml) 0.109 0.117 − 0.016 − 0.025 − 0.163 − 0.169 − 0.007 0.124
IL-23 (pg/ml) −0.051 −0.062 − 0.039 0.010 − 0.079 −0.076 − 0.050 0.232*
IL-33 (pg/ml) 0.016 0.011 −0.096 −0.108 − 0.039 −0.102 − 0.053 0.205
CRP (μg/ml) 0.004 0.009 −0.077 −0.053 − 0.257* −0.256* 0.072 −0.030
Ferritin (μg/L) 0.112 0.157 0.136 0.160 0.093 0.058 −0.191 0.049
  1. * p < .05, **p < .01. IL Interleukin, IFN Interferon, TNF Tumour necrosis factor, MCP Monocyte chemoattractant protein, CRP C-reactive protein, BMD Bone mineral density. Significant values are in bold text