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Table 7 Partial correlations of inflammatory markers with bone health indicators adjusting for age and BMI

From: Inflammatory markers and bone health in postmenopausal women: a cross-sectional overview

 

Spine BMD

Spine

T-score

Hip BMD

Hip T-score

P1NP (ug/L)

CTX-1 (ug/L)

PTH (pmol/L)

25(OH)D3 (nmol/L)

IL-1β (pg/ml)

−0.188

− 0.197

− 0.217

− 0.188

0.010

−0.064

− 0.039

0.092

IFN-α2 (pg/ml)

−0.003

− 0.017

− 0.075

− 0.087

− 0.185

− 0.222*

0.065

0.054

IFN-γ (pg/ml)

0.020

0.008

−0.103

− 0.101

− 0.145

−0.221*

0.028

0.174

TNF-α (pg/ml)

0.183

0.180

0.102

0.092

−0.009

− 0.012

0.064

− 0.079

MCP-1 (pg/ml)

0.084

0.067

0.024

0.027

−0.086

− 0.154

0.037

0.277**

IL-6 (pg/ml)

−0.105

−0.131

− 0.256*

− 0.266*

− 0.222*

− 0.166

− 0.107

0.228*

IL-8 (pg/ml)

0.015

0.005

−0.093

−0.087

0.004

−0.081

− 0.093

0.190

IL-10 (pg/ml)

−0.100

−0.108

− 0.160

− 0.174

− 0.069

− 0.163

− 0.115

0.190

IL-12p70 (pg/ml)

−0.094

− 0.102

− 0.185

− 0.202

− 0.156

− 0.228*

− 0.128

0.158

IL-17A (pg/ml)

−0.057

− 0.067

− 0.049

− 0.011

− 0.062

−0.123

− 0.167

0.240*

IL-18 (pg/ml)

0.109

0.117

− 0.016

− 0.025

− 0.163

− 0.169

− 0.007

0.124

IL-23 (pg/ml)

−0.051

−0.062

− 0.039

0.010

− 0.079

−0.076

− 0.050

0.232*

IL-33 (pg/ml)

0.016

0.011

−0.096

−0.108

− 0.039

−0.102

− 0.053

0.205

CRP (μg/ml)

0.004

0.009

−0.077

−0.053

− 0.257*

−0.256*

0.072

−0.030

Ferritin (μg/L)

0.112

0.157

0.136

0.160

0.093

0.058

−0.191

0.049

  1. * p < .05, **p < .01. IL Interleukin, IFN Interferon, TNF Tumour necrosis factor, MCP Monocyte chemoattractant protein, CRP C-reactive protein, BMD Bone mineral density. Significant values are in bold text