From: Systemic infection and microglia activation: a prospective postmortem study in sepsis patients
Control N = 15 | Septic shock N = 16 | p-value | |
---|---|---|---|
Female n (%) | 7 (46.7) | 5 (31.3) | 0.473 |
Age in years. Median (IQR) | 70.1 (65.2–87.4) | 68.6 (58.9–71.7) | 0.119 |
Living independently. N (%) | 13 (86.7) | 16 (100.0) | 0.226 |
N of chronic illnesses. Median (IQR) | 3 (1–4) | 2 (0–3) | 0.060 |
Medical history | |||
Diabetes. N (%) | 4 (26.7) | 4 (25.0) | 1.00 |
Hypertension. N (%) | 11 (73.3) | 10 (62.5) | 0.704 |
Heartfailure (NYHA ≥II). N (%) | 6 (40.0) | 1 (6.3) | 0.037 |
Cardiac other. N (%) | 11 (73.3) | 8 (50.0) | 0.273 |
Peripheral vasculopathy. N (%) | 2 (13.3) | 0 | 0.226 |
Dyslipidemia. N (%) | 6 (40.0) | 2 (12.5) | 0.113 |
CVA. N (%) | 3 (20.0) | 1 (6.3) | 0.333 |
Chronic kidney disease (≥G3). N (%) | 5 (33.3) | 3 (18.8) | 0.433 |
Livercirrhosis. N (%) | 0 | 1 (6.3) | 0.325 |
COPD (GOLD≥2). N (%) | 0 | 2 (12.5) | 0.333 |
Inflammatory disease. N (%) | 3 (20.0) | 1 (6.3) | 0.704 |
Malignancy. N (%) | 4 (26.7) | 6 (37.5) | |
Immune compromised. N (%) | 0 | 0 | |
Alcohol or drug abuse. N (%) | 1 (6.7) | 1 (6.3) | 1.00 |
N regular medication. Median (IQR) | 7.5 (5.3–12.5) | 6 (2.0–12.0) | 0.223 |
Anticholinergic scores. Median (IQR) | |||
ACB score. | 2.5 (1.0–3.0) | 1.0 (0.0–2.8) | 0.146 |
ARS score. | 0 (0–0) | 0 (0–0.75) | 0.423 |