Fig. 2

Genderwise comparison of the distributions of the CD19+ B cell subpopulation proportions and the CD19+ subpopulation gating strategy. a Median B cell subpopulation proportions in nonagenarian males and young males. P-values of the significances for the aging-associated differences were 0.113, 0.159, 0.057 and 0.139 for CD27+ IgD-, CD27+ IgD+, CD27 -IgD+ and CD27- IgD-, respectively. b Median B cell subpopulation proportions in nonagenarian females and young females. P-values of the significances for the aging-associated differences were 0.083, 0.002, 0.022 and 0.009 for CD27+ IgD-, CD27+ IgD+, CD27 -IgD+ and CD27- IgD-, respectively. Error bars represent 95% confidence interval. c Median B cell subpopulation cell numbers in nonagenarian males and young males. d Median B cell subpopulation cell numbers in nonagenarian females and young females. e Gating strategy of CD19+ B cell subpopulations. Representative samples from a young adult and a nonagenarian donor are shown. Numbers indicate population frequencies