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Fig. 3 | Immunity & Ageing

Fig. 3

From: The presence of CLL-associated stereotypic B cell receptors in the normal BCR repertoire from healthy individuals increases with age

Fig. 3

BCR repertoire analysis in naive mature B cells upon aging. a. Comparison of HCDR3 lengths in < 50, 50–70, and 70 + y age categories. Statistical significance was determined using the Kolmogorov-Smirnov test. b. Circos plots of the combination of IGHV-IGHJ gene usage in < 50, 50–70, and 70 + y age categories. c. Differences in IGHV gene usage frequencies upon aging. Statistical significance between different age groups was determined using the two-way ANOVA test (with Bonferroni multiple comparisons correction); *, p < 0.05; **, p < 0.01; ***, p < 0.001; ****, p < 0.0001

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