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Table 2 Hazard ratios for the individual associations of hs-CRP levels and cognitive status with all-cause mortality (N = 1447)

From: Combined associations of hs-CRP and cognitive function with all-cause mortality among oldest-old adults in Chinese longevity areas: a prospective cohort study

hs-CRP (mg/L)

Model 1

Model 1 + cognition

Model 2

Model 2 + cognitiona

Cut-off at 3.0 mg/L

 Low hs-CRP (≤3.0 mg/L)

1

1

1

1

 High hs-CRP (> 3.0 mg/L)

1.75 (1.30, 2.37)

1.67 (1.19, 2.34)

1.76 (1.30, 2.37)

1.64 (1.17, 2.30)

Cut-offs by quartiles

 Q1(< 0.41)

1

1

1

1

 Q2(0.41–1.05)

1.32 (0.87, 2.01)

1.36 (0.87, 2.12)

1.49 (0.95, 2.35)

1.47 (0.94, 2.30)

 Q3(1.06–3.05)

1.24 (0.82, 1.89)

1.14 (0.71, 1.83)

1.40 (0.89, 2.19)

1.19 (0.73, 1.92)

 Q4(≥3.06)

2.20 (1.45, 3.32)

2.02 (1.25, 3.26)

2.39 (1.53, 3.73)

2.10 (1.30, 3.39)

P for trend

< 0.001

0.009

< 0.001

0.008

Cognition groups

Model 1

Model 1 + hs-CRP

Model 2a

Model 2 + hs-CRPa

Normal cognition

1

1

1

1

Cognitive impairment

2.72 (1.90, 3.91)

2.29 (1.63, 3.21)

2.73 (1.91, 3.91)

2.30 (1.64, 3.21)

  1. Model 1 adjusted for age and sex; model 2 further adjusted for education, drinking, smoking, marital status, regular exercise, medication, BMI, central obesity, self-reported history of hypertension, diabetes mellitus, heart disease, stroke and cerebrovascular disease, respiratory disease and cancer
  2. aEducation was not included